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MIRAGE
phospholipase A2 group IIA

Summary
Gene Symbol
  • PLA2G2A
Organism
Gorilla gorilla gorilla (western lowland gorilla)
NCBI Gene
101151354
KEGG Gene ID
ggo:101151354
PubChem
101151354
Annotation
Keyword
  • Bacteriolytic enzyme
  • Calcium
  • Disulfide bond
  • Hydrolase
  • Lipid metabolism
  • Metal-binding
  • Reference proteome
  • Secreted
  • Signal
Proteins
Displaying 1 entry
UniProt Protein Name
G3QZ00
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
phospholipid metabolic process
lipid catabolic process
arachidonic acid secretion
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
phospholipase A2
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
arachidonic acid secretion
calcium ion binding
calcium-dependent phospholipase A2 activity
hydrolase activity
lipid metabolic process
metal ion binding
phospholipid binding
phospholipid metabolic process
Displaying all 4 entries
InterPro
Phospholipase A2 domain superfamily
Phospholipase A2 domain
Phospholipase A2, histidine active site
Phospholipase A2
Rhea

RHEA:15801

H2O + a 1,2-diacyl-sn-glycero-3-phosphocholine
H+ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine
Enzyme
PMID

RHEA:36231

H2O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine
H+ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 42 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5320 HUMAN47855
18780 MOUSE41569
29692 RATNO32904
456587 PANTR20129
507201 BOVIN25313
521383 BOVIN25311
615045 BOVIN25314
704520 MACMU21255
100125947 BOVIN25313
100135599 CAVPO12244
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025