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phospholipid transfer protein

Summary

Gene Symbol

Pltp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18830

PubChem

18830

Alliance of Genome Resources

MGI:103151

Annotation

Keyword

Disulfide bond
Glycoprotein
Lipid transport
Nucleus
Reference proteome
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3UE59
Q3UFS5
P55065	Lipid transfer protein II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 18 in total

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GO Term	Evidence Code	PMID
phospholipid transport	IBA
phospholipid transport	IEA
sterol transport	IEA
flagellated sperm motility	IMP	16467369
high-density lipoprotein particle remodeling	ISS

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

heterocycle biosynthetic process [inference]

vitamin E biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

vitamin E biosynthetic process

organic hydroxy compound biosynthetic process [inference]

vitamin E biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

heterocycle biosynthetic process [inference]

vitamin E biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

vitamin E biosynthetic process

vitamin E metabolic process [inference]

vitamin E biosynthetic process

small molecule metabolic process [inference]

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

vitamin E metabolic process [inference]

vitamin E biosynthetic process

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

vitamin E metabolic process [inference]

vitamin E biosynthetic process

organic cyclic compound biosynthetic process [inference]

vitamin E biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

vitamin E biosynthetic process

organic hydroxy compound biosynthetic process [inference]

vitamin E biosynthetic process

organic hydroxy compound metabolic process [inference]

vitamin E metabolic process [inference]

vitamin E biosynthetic process

organic hydroxy compound biosynthetic process [inference]

vitamin E biosynthetic process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

cellular metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

heterocycle biosynthetic process [inference]

vitamin E biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

vitamin E biosynthetic process

vitamin E metabolic process [inference]

vitamin E biosynthetic process

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

membrane organization [inference]

intermembrane lipid transfer

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

organophosphate ester transport [inference]

phospholipid transport

organic hydroxy compound transport [inference]

sterol transport

carbohydrate derivative transport [inference]

glycolipid transport

nitrogen compound transport [inference]

amide transport [inference]

ceramide transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular region	ISS
extracellular region	ISO
extracellular space	IBA
extracellular space	HDA	24006456
nucleus	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
high-density lipoprotein particle binding	ISS
high-density lipoprotein particle binding	ISO
lipid binding
phosphatidylethanolamine binding	ISO
phosphatidylethanolamine binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity [inference]

phosphatidylcholine transporter activity [inference]

phosphatidylcholine transfer activity

phospholipid transfer activity

sterol transporter activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

sphingolipid transporter activity [inference]

sphingolipid transfer activity [inference]

ceramide transfer activity

cerebroside transfer activity

sphingomyelin transfer activity

lipid transfer activity [inference]

glycolipid transfer activity [inference]

cerebroside transfer activity

phospholipid transfer activity

sterol transfer activity [inference]

cholesterol transfer activity

sphingolipid transfer activity [inference]

ceramide transfer activity

cerebroside transfer activity

sphingomyelin transfer activity

diacylglyceride transfer activity

binding [inference]

protein binding [inference]

very-low-density lipoprotein particle binding

lipid binding

phospholipid binding [inference]

diacylglycerol binding

sphingolipid binding [inference]

ceramide binding

amide binding [inference]

ceramide binding

ion binding [inference]

anion binding [inference]

cation binding [inference]

phosphatidylcholine binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10140	dry eye syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	671	WB:WBGene00008512
Caenorhabditis elegans	3929	WB:WBGene00016951
Homo sapiens	5360	Xenbase:XB-GENE-981861	HUMAN57329
Caenorhabditis elegans	16803	WB:WBGene00022627
Xenopus tropicalis	18830	Xenbase:XB-GENE-981861
Rattus norvegicus	181720	RGD:1306695
Caenorhabditis elegans	254240	WB:WBGene00022627
Caenorhabditis elegans	270757	WB:WBGene00022627
Caenorhabditis elegans	296321	WB:WBGene00008512
Rattus norvegicus	296371		RATNO27144