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Gamma-aminobutyric acid type B receptor subunit 2

Summary

Gene Symbol

gbb-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

191240

PubChem

191240

Alliance of Genome Resources

WB:WBGene00022675

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
G5ECB2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IMP	18614679
G protein-coupled receptor signaling pathway	IEA
gamma-aminobutyric acid signaling pathway	IBA
response to xenobiotic stimulus	IMP	18614679
negative regulation of synaptic transmission, cholinergic	IMP	18614679

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

signal transduction [inference]

G protein-coupled receptor signaling pathway

response to stimulus [inference]

response to chemical [inference]

response to xenobiotic stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

negative regulation of synaptic transmission, cholinergic

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

regulation of locomotion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

negative regulation of synaptic transmission, cholinergic

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, cholinergic

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA
G protein-coupled receptor heterodimeric complex	IBA
G protein-coupled GABA receptor complex	TAS	18614679

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

GABA receptor complex [inference]

G protein-coupled GABA receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IEA
G protein-coupled GABA receptor activity	IMP	18614679
G protein-coupled GABA receptor activity	IBA
G protein-coupled GABA receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled GABA receptor activity

GABA receptor activity [inference]

G protein-coupled GABA receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
G protein-coupled GABA receptor activity
gamma-aminobutyric acid signaling pathway

Displaying **all 4** entries
InterPro
GPCR family 3, C-terminal
GPCR family 3, GABA-B receptor
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	9568	Xenbase:XB-GENE-5815161
Xenopus tropicalis	83633	Xenbase:XB-GENE-5815161
Xenopus tropicalis	191240	Xenbase:XB-GENE-5815161
Xenopus tropicalis	242425	Xenbase:XB-GENE-5815161