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MIRAGE
interferon alpha and beta receptor subunit 2
Summary
- Gene Symbol
-
- IFNAR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell surface receptor signaling pathway | ||
| receptor signaling pathway via JAK-STAT | ||
| response to virus | ||
| response to interferon-alpha | ||
| response to interferon-alpha |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| type I interferon receptor activity | ||
| type I interferon receptor activity | ||
| protein binding | ||
| JAK pathway signal transduction adaptor activity | ||
| protein kinase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Interferon alpha/beta receptor 2
- Functional Category
-
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| interleukin-22 receptor activity |
| type I interferon receptor activity |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
| Interferon/interleukin receptor domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111994 | immunodeficiency 45 | |
| DOID:2043 | hepatitis B |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3455 | Xenbase:XB-GENE-494539 | ||
| 15976 | Xenbase:XB-GENE-855851 | MOUSE17641 | |
| 58985 | ZFIN:ZDB-GENE-071120-6 | ||
| 163702 | ZFIN:ZDB-GENE-070905-2 | ||
| 230828 | ZFIN:ZDB-GENE-071120-6 | ||
| 242700 | ZFIN:ZDB-GENE-070905-2 | ||
| 282258 | BOVIN14177 | ||
| 443363 | SHEEP01173 | ||
| 473965 | PANTR25571 | ||
| 686326 | RATNO04329 |
