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G37184KW

Summary

GlyTouCan ID: G37184KW
IUPAC Condensed: Neu5Ac(a2-8)Neu5Ac(a2-3)[Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs: GD1b
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 1289.44

External Links

GlyGen

G37184KW

ChEBI

59222

PubChem Compound

45266846

PubChem Substance

252286914

CarbBank

3D Structures

GLYCAM: Neup5Aca2-8Neup5Aca2-3[DGalpb1-3DGalpNAcb1-4]DGalpb1-4DGlcpb1-OH

GlycoShape

G37184KW

Organisms

Displaying entries **6 - 10** of 37 in total

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Organisms	Evidence
Soricidae (shrews)	GlyTouCan(glycome-db)
Globicephala macrorhynchus (short-finned pilot whale)	GlyTouCan(glycome-db)
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Gallus gallus (chicken)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Whippomorpha [inference]

Cetacea (whales) [inference]

Mysticeti (baleen whales) [inference]

Balaenopteridae (rorquals) [inference]

Balaenoptera [inference]

Odontoceti (tooth whales) [inference]

Delphinidae (marine dolphins) [inference]

Delphinus [inference]

Delphinus delphis (saddleback dolphin)

Globicephala (pilot whales) [inference]

Globicephala macrorhynchus (short-finned pilot whale)

Stenella [inference]

Stenella coeruleoalba (striped dolphin)

Orcinus [inference]

Orcinus orca (killer whale)

Tursiops [inference]

Tursiops truncatus (common bottlenose dolphin)

Physeteridae (sperm whales) [inference]

Physeter [inference]

Physeter catodon (sperm whale)

Phocoenidae (porpoises) [inference]

Phocoenoides [inference]

Phocoenoides dalli (Dall's porpoise)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Eulipotyphla (hedgehogs, shrews, moles and others) [inference]

Soricidae (shrews)

Crocidurinae [inference]

Suncus (musk shrews) [inference]

Suncus murinus (house shrew)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids)

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Cyprinus [inference]

Cyprinus carpio (common carp)

Carassius [inference]

Carassius auratus (goldfish)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates) [inference]

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA6	CMP-Neu5Ac	G37184KW	Cer	11980897 16120058
ST3GAL6	CMP-Neu5Ac	G37184KW	ceramide	10206952
ST8SIA3	CMP-Neu5Ac	G37184KW	Cer	7782326
B3GALT4	UDP-Gal	G37184KW	Cer	9312075

KEGG BRITE Database

KEGG ID

G00115

Enzyme

References

7553668

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05949	2.4.3.2	G37184KW	G40183QN
R05948	2.4.1.62	G02657AK	G37184KW

GlycoEpitope

Epitope ID: EP0059

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7b:b-dgal-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
6:2o(4+1)7d
7:7d(2+1)8n
8:7o(3+1)9d

WURCS

WURCS=2.0/4,6,5/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-3-4-2/a4-b1_b3-c2_b4-e1_c8-d2_e3-f1

Literature

Displaying entries **21 - 28** of 28 in total

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PubMed ID	Title	First Author	Publication Date	Source
7685064	Localization of GM1 and GD1b antigens in the human peripheral nervous system	Kusunoki S	1993 Jul	GlyGen GlycoEpitope
8410057	Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and gangliosides	Moncó JCG	1993 Jul	PubChem
8490240	Differential distribution of major gangliosides in rat central nervous system detected by specific monoclonal antibodies	Kotani M	1993 Apr	GlyGen GlycoEpitope
1371229	Generation of one set of monoclonal antibodies specific for b-pathway ganglio-series gangliosides	Ozawa H	1992 Jan 24	GlyGen GlycoEpitope
1828263	Immunoprecipitation of membrane proteins from rat basophilic leukemia cells by the antiganglioside monoclonal antibody AA4	Stephan V	1991 Jun 15	GlyGen GlycoEpitope
2376746	Anticardiolipin antibodies in patients with rabies vaccination induced neurological complications and other neurological diseases	Chaleomchan W	1990 May	PubChem
3170507	Different fine binding specificities of monoclonal antibodies to disialosylganglioside GD2	Tai T	1988 Apr	GlyGen GlycoEpitope
4029397	A monoclonal antibody reacting specifically with ganglioside GD1b in human brain	Fredman P	1985 Sep 09	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **1 - 5** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Attenuation of interleukin 2 signal in the spleen cells of complex ganglioside-lacking mice.	Zhao J Furukawa K Fukumoto S Okada M Furugen R Miyazaki H Takamiya K Aizawa S Shiku H Matsuyama T Furukawa K	J Biol Chem	1999 May 14	10318776
Activation of human T lymphocytes by ganglioside-containing liposomes.	Yanagihara K Kato E Hitomi S Sunamoto J Wada H	Glycoconj J	1999 Jan	10580651
Synthesis of a photoreactive, radiolabelled derivative of the oligosaccharide of GM1 ganglioside.	Pacuszka T Fishman PH	Glycobiology	1992 Jun	1498422
Generation of one set of monoclonal antibodies specific for b-pathway ganglio-series gangliosides.	Ozawa H Kotani M Kawashima I Tai T	Biochim Biophys Acta	1992 Jan 24	1371229
Ganglioside-binding proteins in skeletal and cardiac muscle.	Chan KF Liu Y	Glycobiology	1991 Mar	1823162

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements