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G39023AU

Summary

GlyTouCan ID: G39023AU
IUPAC Condensed: Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-
Motifs: Lea Lewis a Type 1 LN
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 529.2

External Links

GlyGen

G39023AU

ChEBI

59295

PubChem Compound

5288293

PubChem Substance

252276473

CarbBank

3D Structures

GLYCAM: DGalpb1-3[LFucpa1-4]DGlcpNAcb1-OH

GlycoShape

G39023AU

Displaying 1 entry
Archetype	α	β
G01706RV	G65372SM	G39023AU

Organisms

Displaying entries **1 - 5** of 14 in total

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Organisms	Evidence
Felis catus (domestic cat)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyTouCan(glycome-db)
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)
Human immunodeficiency virus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

Viruses [inference]

Riboviria [inference]

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

Human immunodeficiency virus 1

cellular organisms [inference]

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Helicobacteraceae [inference]

Helicobacter [inference]

Helicobacter pylori

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Rattus

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Lepidosauria (lepidosaurs) [inference]

Squamata (squamates) [inference]

Bifurcata (split-tongued squamates) [inference]

Unidentata [inference]

Episquamata [inference]

Toxicofera [inference]

Serpentes (snakes) [inference]

Colubroidea [inference]

Elapidae [inference]

Elapinae [inference]

Naja

Naja kaouthia (monocled cobra)

GlycoGene Database (GGDB)

Displaying **all 2** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
FUT5	GDP-Fuc	G00056MO	R	G39023AU	R	8780523
FUT3	GDP-Fuc	G00056MO	R	G39023AU	R	7721776

Displaying **all 3** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
FUT5	GDP-Fuc	G00056MO	R	G39023AU	R	8780523
FUT3	GDP-Fuc	G00056MO	R	G39023AU	R	7721776
B3GLCT	UDP-Glc	G39023AU	[beta]-pNp	G71649FF	[beta]-pNp	16899492

KEGG BRITE Database

KEGG ID

G10738

GlycoEpitope

Epitope ID: EP0007

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d

WURCS

WURCS=2.0/3,3,2/[a2122h-1b_1-5_2*NCC/3=O][a2112h-1b_1-5][a1221m-1a_1-5]/1-2-3/a3-b1_a4-c1

Literature

Displaying entries **1 - 10** of 33 in total

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PubMed ID	Title	First Author	Publication Date	Source
30333166	Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths	Qian Y	2019 Jan 01	PubChem
31266803	Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens	Hobbs JK	2019 Aug 23	PubChem
27303392	Genomic Rearrangements and Functional Diversification of lecA and lecB Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed against Pseudomonas aeruginosa	Boukerb AM	2016 May 31	PubChem
30155149	The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery	Sommer R	2016 Aug 01	PubChem
26147716	A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface	Liu W	2015 Jul 06	PubChem
24648450	Structural Analysis of Determinants of Histo-Blood Group Antigen Binding Specificity in Genogroup I Noroviruses	Shanker S	2014 Jun	PubChem
22855491	Structural Basis for the Recognition of Lewis Antigens by Genogroup I Norovirus	Kubota T	2012 Oct 15	PubChem
22451675	1,3-1,4-α-l-Fucosynthase That Specifically Introduces Lewis a/x Antigens into Type-1/2 Chains	Sakurama H	2012 May 11	PubChem
22160312	Helicobacter pylori isolates from Greek children express type 2 and type 1 Lewis and α1,6-glucan antigens in conjunction with a functional type IV secretion system	Altman E	2012 Apr 01	PubChem
19162326	Characterization of murine MGL1 and MGL2 C-type lectins: Distinct glycan specificities and tumor binding properties	Singh SK	2009 Mar	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **6 - 9** of 9 in total

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Title	Authors	Source	Publication Date	PubMed ID
In vitro alpha1-3 or alpha1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI.	Nimtz M Grabenhorst E Gambert U Costa J Wray V Morr M Thiem J Conradt HS	Glycoconj J	1998 Sep	10052591
Purification and characterization of a membrane-bound and a secreted mucin-type glycoprotein carrying the carcinoma-associated sialyl-Lea epitope on distinct core proteins.	Baeckström D Hansson GC Nilsson O Johansson C Gendler SJ Lindholm L	J Biol Chem	1991 Nov 15	1718981
An enzyme-linked immunosorbent assay for the measurement of Lewis blood-group alpha-(1----4)-fucosyltransferase activity.	Palcic MM Ratcliffe RM Lamontagne LR Good AH Alton G Hindsgaul O	Carbohydr Res	1990 Feb 25	2346934
Isolation and characterization of a Lewis b-active lectin from Griffonia simplicifolia seeds.	Shibata S Goldstein IJ Baker DA	J Biol Chem	1982 Aug 25	7107573

GlyTouCan

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Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

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Acknowledgements