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MIRAGE
G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
CarbBank
3D Structures
GLYCAM
DGalpNAca1-OH
GlycoShape
G57321FI
Organisms
Displaying entries 1 - 5 of 26 in total
Organisms Evidence
Ovis aries (sheep)
Cricetulus griseus (Chinese hamster)
Mus musculus (house mouse)
Bos taurus (domestic cattle)
Escherichia coli
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC2 CMP-Neu5Ac
G57321FI
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[alpha]-Bz
ST6GALNAC2 CMP-Neu5Ac
G57321FI
Ser/Thr
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R05908
R05910
R05911
R05909
Core Protein
Displaying entries 701 - 710 of 819 in total
UniProt ID Protein Name Reference Source
Q9H239 Matrix metalloproteinase-28
Q9H2A7 C-X-C motif chemokine 16
Q9H2A9 Carbohydrate sulfotransferase 8
Q9H3R2 Mucin-13
Q9H467 CUE domain-containing protein 2
Q9H4A9 Dipeptidase 2
Q9H4F1 Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase
Q9H4F8 SPARC-related modular calcium-binding protein 1
Q9H5V8 CUB domain-containing protein 1
Q9H5Y7 SLIT and NTRK-like protein 6
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 41 - 50 of 57 in total
Pathway Name Organism
Ficolins bind to repetitive carbohydrate structures on the target cell surface Sus scrofa
Initial triggering of complement Canis familiaris
Initial triggering of complement Rattus norvegicus
Initial triggering of complement Mus musculus
Initial triggering of complement Homo sapiens
Initial triggering of complement Bos taurus
Initial triggering of complement Xenopus tropicalis
Initial triggering of complement Sus scrofa
Initial triggering of complement Gallus gallus
Lectin pathway of complement activation Sus scrofa
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 1011 - 1020 of 2052 in total
PubMed ID Title First Author Publication Date Source
10599506 [Cellular localization of mucin type receptors determined with novel GalNac/Gal-specific lectin from sea mussel Crenomytilus grayanus in human colon tumors] Furtak VA 1999 Oct
  • PubChem
10600032 A Monoclonal Antibody Against Hamster Tracheal Mucin, Which RecognizesN-Acetyl-Galactosamine Containing Carbohydrate Chains as an Epitope Jo M 1999 Oct
  • PubChem
10471478 Inhibition of bovine sperm‐oocyte fusion by the carbohydrate GalNAc Gougoulidis T 1999 Oct
  • PubChem
10622728 Binding of Bacillus thuringiensis Cry1Ac toxin to Manduca sexta aminopeptidase‐N receptor is not directly related to toxicity Jenkins JL 1999 Nov 30
  • PubChem
10536037 Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens Ikehara Y 1999 Nov 01
  • PubChem
10406203 Mutual separation of hinge-glycopeptide isomers bearing five N-acetylgalactosamine residues from normal human serum immunoglobulin A1 by capillary electrophoresis Iwase H 1999 May 28
  • PubChem
10329456 Enzymatic reconstruction of a hybrid glycosaminoglycan containing 6-sulfated, 4-sulfated, and unsulfated N-acetylgalactosamine Takagaki K 1999 May 19
  • PubChem
10318803 The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate Kitagawa H 1999 May 14
  • PubChem
10228146 Tachylectin‐2: crystal structure of a specific GlcNAc/GalNAc‐binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus Beisel HG 1999 May 04
  • PubChem
10382304 'Wave-type' structure of a synthetic hexaglycosylated decapeptide: A part of the extracellular domain of human glycophorin A Schuster O 1999 May
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
  • Danussi C
  • Coslovi A
  • Campa C
  • Mucignat MT
  • Spessotto P
  • Uggeri F
  • Paoletti S
  • Colombatti A
 Glycobiology 2009 Oct 19528665
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.
  • Freire T
  • Lo-Man R
  • Piller F
  • Piller V
  • Leclerc C
  • Bay S
 Glycobiology 2006 May 16449349
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.
  • Zhang Y
  • Iwasaki H
  • Wang H
  • Kudo T
  • Kalka TB
  • Hennet T
  • Kubota T
  • Cheng L
  • Inaba N
  • Gotoh M
  • Togayachi A
  • Guo J
  • Hisatomi H
  • Nakajima K
  • Nishihara S
  • Nakamura M
  • Marth JD
  • Narimatsu H
 J Biol Chem 2003 Jan 3 12407114
Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.
  • Kakiuchi M
  • Okino N
  • Sueyoshi N
  • Ichinose S
  • Omori A
  • Kawabata S
  • Yamaguchi K
  • Ito M
 Glycobiology 2002 Feb 11886841
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.
  • Allen JR
  • Harris CR
  • Danishefsky SJ
 J Am Chem Soc 2001 Mar 7 11456809
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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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