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Beta-2 adrenergic receptor
Summary
- UniProt ID
- P10608
- Gene Symbol
-
- Adrb2
- Adrb2r
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Palmitate
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Schaffer collateral - CA1 synapse |
| glutamatergic synapse |
| neuronal dense core vesicle |
| presynapse |
| endosome |
| early endosome |
| Golgi apparatus |
| apical plasma membrane |
| sarcolemma |
| caveola |
| GO Term |
|---|
| receptor-receptor interaction |
| G-protein alpha-subunit binding |
| adenylate cyclase binding |
| PDZ domain binding |
| ionotropic glutamate receptor binding |
| protein phosphatase 2A binding |
Sequence
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Adrenoceptors | Rattus norvegicus |
| Cargo recognition for clathrin-mediated endocytosis | Rattus norvegicus |
| Clathrin-mediated endocytosis | Rattus norvegicus |
| G alpha (s) signalling events | Rattus norvegicus |
| Ub-specific processing proteases | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11396 | pulmonary edema | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:3021 | acute kidney failure | |
| DOID:552 | pneumonia | |
| DOID:557 | kidney disease | |
| DOID:6000 | congestive heart failure | |
| DOID:820 | myocarditis |
