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TRAF family member associated NFKB activator

Summary

Gene Symbol

TANK

Organism

Homo sapiens (human)

External Links

NCBI Gene

10010

PubChem

10010

Alliance of Genome Resources

HGNC:11562

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Cytoplasm
DNA damage
Host-virus interaction
Phosphoprotein
Reference proteome
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q6NW12
Q92844	TRAF-interacting protein
B2R7S3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

1

2

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GO Term	Evidence Code	PMID
DNA damage response	IMP	25861989
cellular response to DNA damage stimulus	IMP	25861989
signal transduction	TAS	8710854
negative regulation of tumor necrosis factor-mediated signaling pathway	IEA
positive regulation of type I interferon production	IDA	21931631

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

cellular response to ionizing radiation

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

response to interleukin-1 [inference]

cellular response to interleukin-1

cellular response to cytokine stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of ubiquitin-specific protease activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein deubiquitination [inference]

positive regulation of protein deubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of ubiquitin-specific protease activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein deubiquitination [inference]

positive regulation of protein deubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of ubiquitin-specific protease activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein deubiquitination [inference]

positive regulation of protein deubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein deubiquitination

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of hydrolase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of ubiquitin-specific protease activity

regulation of ubiquitin-specific protease activity [inference]

positive regulation of ubiquitin-specific protease activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	IDA	21931631
cytosol	TAS
cytosol	IDA
protein-containing complex	IDA	25861989
serine/threonine protein kinase complex	NAS	21931631

GO Hierarchy

cellular component

protein-containing complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex

cellular anatomical entity [inference]

Displaying entries **6 - 8** of 8 in total

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1

2
GO Term	Evidence Code	PMID
metal ion binding
molecular adaptor activity	IDA	21931631
molecular function inhibitor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

binding [inference]

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

molecular adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

deubiquitinase activator activity

peptidase regulator activity [inference]

peptidase activator activity [inference]

deubiquitinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

deubiquitinase activator activity

molecular function inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

TRAF family member-associated NF-kappa-B activator

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
canonical NF-kappaB signal transduction

Displaying **all 2** entries
InterPro
TRAF family member-associated NF-kappa-B activator
Tbk1/Ikki binding domain

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10010	Xenbase:XB-GENE-483297
Mus musculus	21353	Xenbase:XB-GENE-483297	MOUSE36313
Rattus norvegicus	252961		RATNO28129
Pan troglodytes	459685		PANTR28955
Bos taurus	539513		BOVIN24188
Canis lupus familiaris	608092		CANLF13905
Macaca mulatta	700942		MACMU07182
Monodelphis domestica	100022154		MONDO22995
Ornithorhynchus anatinus	100077165		ORNAN27339
Sus scrofa	100156366		PIGXX09346

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements