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aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Summary
- Gene Symbol
-
- AKR1C1
- Organism
- Pongo abelii (Sumatran orangutan)
External Links
- NCBI Gene
- 100171658
- KEGG Gene ID
- ["pon:100171658"]
- PubChem
- 100171658
Annotation
- Keyword
-
- Cytoplasm
- Lipid metabolism
- NADP
- Oxidoreductase
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5REQ0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| alcohol metabolic process |
|
|
| digestion |
|
|
| bile acid metabolic process |
|
|
| hormone metabolic process |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| estradiol 17-beta-dehydrogenase [NAD(P)+] activity |
|
|
| estradiol 17-beta-dehydrogenase [NAD(P)+] activity |
|
|
| oxidoreductase activity |
|
|
| carboxylic acid binding |
|
|
| bile acid binding |
|
GO Hierarchy
- estradiol 17-beta-dehydrogenase [NAD(P)+] activity
- 3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity
- 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
- androsterone dehydrogenase [NAD(P)+] activity
- 5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity
- androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
- 3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity
- estradiol 17-beta-dehydrogenase [NAD(P)+] activity
- 3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity
- 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
- androsterone dehydrogenase [NAD(P)+] activity
- 5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity
- androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
- 3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity
- indanol dehydrogenase activity
molecular function
catalytic activity [inference]
oxidoreductase activity
steroid dehydrogenase activity [inference]
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]
oxidoreductase activity, acting on CH-OH group of donors [inference]
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- aldo-keto
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| alditol |
| oxidoreductase activity |
| InterPro |
|---|
| Aldo-keto reductase |
| Aldo/keto reductase, conserved site |
| NADP-dependent oxidoreductase domain superfamily |
| NADP-dependent oxidoreductase domain |
Rhea
