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solute carrier family 39 member 8

Summary

Gene Symbol

SLC39A8

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100171966
KEGG Gene ID: pon:100171966
PubChem: 100171966

Annotation

Keyword

Reference proteome
Signal
Transmembrane helix
Zinc transport

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2J8XQV0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
protein N-linked glycosylation
arginine metabolic process
intracellular zinc ion homeostasis	IEA
mercury ion transport	IEA
intracellular monoatomic cation homeostasis	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte adhesion to arterial endothelial cell

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

arginine metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

arginine metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

mercury ion transport

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport [inference]

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

plasma membrane selenite transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

manganese ion homeostasis [inference]

intracellular manganese ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

intracellular zinc ion homeostasis

manganese ion homeostasis [inference]

intracellular manganese ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron import into cell [inference]

iron ion import across plasma membrane

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

manganese ion transport [inference]

manganese ion transmembrane transport [inference]

mitochondrial manganese ion transmembrane transport

zinc ion transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

cadmium ion transport [inference]

cadmium ion transmembrane transport

mercury ion transport

monoatomic cation transmembrane transport [inference]

mercury ion transport

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport [inference]

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

mercury ion transport

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport [inference]

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

mercury ion transport

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport [inference]

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

plasma membrane selenite transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

establishment of localization in cell [inference]

iron import into cell [inference]

iron ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of biological quality [inference]

regulation of membrane potential

detoxification [inference]

detoxification of inorganic compound [inference]

detoxification of cadmium ion [inference]

cellular detoxification of cadmium ion

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lysosomal membrane	IEA
plasma membrane	IEA
basolateral plasma membrane	IEA
apical plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

plasma membrane region [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	IEA
monoatomic cation:bicarbonate symporter activity	IEA
zinc:bicarbonate symporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

zinc:bicarbonate symporter activity

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

zinc:bicarbonate symporter activity

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

zinc:bicarbonate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

zinc:bicarbonate symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

solute carrier family 39 member 8

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
metal ion transmembrane transporter activity
monoatomic cation
zinc ion transmembrane transporter activity

Displaying 1 entry
InterPro
Zinc/iron permease

KEGG BRITE Database

Orthology

K14714

Name

solute carrier family 39 (zinc transporter), member 8

References

12504855

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements