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oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Callithrix jacchus (white-tufted-ear marmoset)

External Links

NCBI Gene: 100386666
KEGG Gene ID: cjc:100386666
PubChem: 100386666

Annotation

Keyword

Isopeptide bond
Nucleus
Oxidoreductase
Reference proteome
Thiamine pyrophosphate
Transit peptide
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
U3FNY3	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
U3DCU9	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
F6XLN9	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
F6WZI4	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202
oxoglutarate dehydrogenase complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dehydrogenase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

Displaying **all 5** entries
Gene Ontology
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
oxidoreductase activity
oxoglutarate dehydrogenase (succinyl-transferring) activity
thiamine pyrophosphate binding
tricarboxylic acid cycle

Displaying **all 7** entries
InterPro
2-oxoglutarate dehydrogenase E1 component, N-terminal domain
2-oxoglutarate dehydrogenase E1 component
Dehydrogenase, E1 component
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Thiamin diphosphate-binding fold
Transketolase-like, pyrimidine-binding domain

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

Rhea

RHEA:12188

H⁺ + 2-oxoglutarate

CO₂

Enzyme

1.2.4.2

PMID

Ortholog

Displaying entries **101 - 105** of **105** in total

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Species	Gene ID	Orthologous MAtrix
Rhinolophus ferrumequinum	117012136	RHIFE27131
Balaenoptera musculus	118900804	BALMU12739
Panthera leo	122205138	PANLE22407
Ursus americanus	123789468	URSAM11380
Bos taurus	132342072	BOVIN28240

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements