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prostaglandin E synthase

Summary

Gene Symbol

PTGES

Organism

Saimiri boliviensis (Bolivian squirrel monkey)

External Links

NCBI Gene: 101029318
KEGG Gene ID: ["sbq:101029318"]
PubChem: 101029318

Annotation

Keyword

Cytoplasm
Isomerase
Oxidoreductase
Prostaglandin biosynthesis
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6T0L0	Glutathione peroxidase PTGES Glutathione transferase PTGES Microsomal prostaglandin E synthase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
prostaglandin biosynthetic process	IEA
cell population proliferation
negative regulation of cell population proliferation
sensory perception of pain	IEA
cyclooxygenase pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonate metabolic process [inference]

cyclooxygenase pathway

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

arachidonate metabolic process [inference]

cyclooxygenase pathway

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

arachidonate metabolic process [inference]

cyclooxygenase pathway

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonate metabolic process [inference]

cyclooxygenase pathway

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

arachidonate metabolic process [inference]

cyclooxygenase pathway

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

olefinic compound metabolic process [inference]

arachidonate metabolic process [inference]

cyclooxygenase pathway

cell population proliferation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of secretion [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

regulation of secretion by cell [inference]

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of prostaglandin secretion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of fever generation

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of fever generation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of secretion by cell [inference]

regulation of prostaglandin secretion [inference]

positive regulation of prostaglandin secretion

positive regulation of secretion by cell [inference]

positive regulation of prostaglandin secretion

regulation of multicellular organismal process [inference]

regulation of heat generation [inference]

regulation of fever generation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nuclear envelope lumen	IEA
endoplasmic reticulum membrane	IEA
membrane	IEA
perinuclear region of cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

nuclear envelope lumen

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glutathione transferase activity	IEA
glutathione peroxidase activity	IEA
prostaglandin-D synthase activity	IEA
glutathione binding	IEA
prostaglandin-E synthase activity	IEA