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dihydrolipoamide dehydrogenase

Summary

Gene Symbol

Organism

Saimiri boliviensis (Bolivian squirrel monkey)

External Links

NCBI Gene: 101050596
KEGG Gene ID: ["sbq:101050596"]
PubChem: 101050596

Annotation

Keyword

Acetylation
Cytoplasmic vesicle
Disulfide bond
FAD
Flagellum
Mitochondrion
NAD
Nucleotide-binding
Nucleus
Oxidoreductase
Phosphoprotein
Redox-active center
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6TNN9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
pyruvate decarboxylation to acetyl-CoA	IEA
pyruvate metabolic process	IEA
2-oxoglutarate metabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process

pyruvate decarboxylation to acetyl-CoA

dicarboxylic acid metabolic process [inference]

2-oxoglutarate metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	IEA
nucleus	IEA
mitochondrion	IEA
mitochondrial matrix	IEA
motile cilium	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle heteromeric enzyme complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

alpha-ketoacid dehydrogenase complex [inference]

transferase complex [inference]

oxoglutarate dehydrogenase complex

acetyltransferase complex [inference]

pyruvate dehydrogenase complex

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dihydrolipoyl dehydrogenase (NADH) activity	IEA
flavin adenine dinucleotide binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [inference]

dihydrolipoyl dehydrogenase (NADH) activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00382

Name

dihydrolipoyl dehydrogenase [EC:1.8.1.4]

References

Rhea

RHEA:15045

NAD⁺

H⁺ + NADH

Enzyme

1.8.1.4

PMID

RHEA:33059

(R)-dihydrolipoamide + NAD⁺

H⁺ + NADH + (R)-lipoamide

Enzyme

1.8.1.4

PMID

13767908

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements