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Repository for lectin-assisted multimodality data

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Tools

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Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

phosphoenolpyruvate carboxykinase 1

Summary

Gene Symbol

PCK1

Organism

Anas platyrhynchos (mallard)

External Links

NCBI Gene: 101793637
KEGG Gene ID: ["apla:101793637"]
PubChem: 101793637

Annotation

Keyword

Cytoplasm
Decarboxylase
GTP-binding
Gluconeogenesis
Kinase
Manganese
Metal-binding
Phosphoprotein
Pyruvate
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
R0LQQ0	Serine-protein kinase PCK1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

1

2

3

4

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Last »
GO Term	Evidence Code	PMID
lactate metabolic process
gluconeogenesis	IEA
oxaloacetate metabolic process	IEA
regulation of gluconeogenesis
vitellogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

glycerol metabolic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

glycerol catabolic process

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process

short-chain fatty acid catabolic process [inference]

propionate catabolic process

lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

alcohol metabolic process [inference]

polyol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

glycerol catabolic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process

pyruvate metabolic process [inference]

glycerol biosynthetic process from pyruvate

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process

short-chain fatty acid catabolic process [inference]

propionate catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

dicarboxylic acid metabolic process [inference]

oxaloacetate metabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process [inference]

glycerol biosynthetic process from pyruvate

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cytoplasm organization [inference]

vitellogenesis

reproductive process [inference]

developmental process involved in reproduction [inference]

eggshell formation

multicellular organismal reproductive process [inference]

reproductive behavior [inference]

egg-laying behavior

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

behavior [inference]

reproductive behavior [inference]

egg-laying behavior

developmental process [inference]

developmental process involved in reproduction [inference]

eggshell formation

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis

anatomical structure formation involved in morphogenesis [inference]

eggshell formation

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

response to stimulus [inference]

response to stress [inference]

response to starvation

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to nutrient levels [inference]

response to starvation

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to organophosphorus [inference]

response to cAMP

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to cAMP

response to alcohol [inference]

response to ethanol [inference]

cellular response to ethanol

cellular response to alcohol [inference]

cellular response to ethanol

response to ketone [inference]

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphoenolpyruvate carboxykinase (GTP) activity	IEA
GTP binding	IEA
kinase activity
manganese ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

phosphoenolpyruvate carboxykinase activity [inference]

phosphoenolpyruvate carboxykinase (GTP) activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphoenolpyruvate carboxykinase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **1 - 10** of 17 in total

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Gene Ontology
GTP binding
carboxy-lyase activity
cellular response to dexamethasone stimulus
cellular response to glucose stimulus
cellular response to insulin stimulus
gluconeogenesis
glycerol biosynthetic process from pyruvate
hepatocyte differentiation
lyase activity
manganese ion binding

Displaying **all 6** entries
InterPro
Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain
Phosphoenolpyruvate carboxykinase, C-terminal
Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal
Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site
Phosphoenolpyruvate carboxykinase, GTP-utilising
Phosphoenolpyruvate carboxykinase, N-terminal

KEGG BRITE Database

Orthology

K01596

Name

phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]

References

Rhea

oxaloacetate + GTP

CO₂ + GDP + phosphoenolpyruvate

Enzyme

4.1.1.32

PMID

oxaloacetate + ITP

CO₂ + IDP + phosphoenolpyruvate

Enzyme

4.1.1.32

PMID

11851336

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026