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3-hydroxyacyl-CoA dehydratase 3

Summary

Gene Symbol

HACD3

Organism

Macaca fascicularis (crab-eating macaque)

External Links

NCBI Gene: 101865117
KEGG Gene ID: mcf:101865117
PubChem: 101865117

Annotation

Keyword

Coiled coil
Endoplasmic reticulum
Fatty acid biosynthesis
Lyase
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
I7GJV7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
JNK cascade
Rho protein signal transduction
sphingolipid biosynthetic process	IEA	30032202 http://purl.obolibrary.org/obo/go/references/0000118
fatty acid elongation	IEA	30032202 http://purl.obolibrary.org/obo/go/references/0000107 http://purl.obolibrary.org/obo/go/references/0000118
very long-chain fatty acid biosynthetic process	IEA	30032202 http://purl.obolibrary.org/obo/go/references/0000107 http://purl.obolibrary.org/obo/go/references/0000118

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

small GTPase-mediated signal transduction [inference]

Rho protein signal transduction

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

positive regulation of biological process [inference]

positive regulation of viral process [inference]

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of viral process [inference]

regulation by virus of viral protein levels in host cell [inference]

positive regulation by virus of viral protein levels in host cell

positive regulation of viral process [inference]

regulation of viral life cycle [inference]

regulation of viral genome replication [inference]

positive regulation of viral genome replication

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

small GTPase-mediated signal transduction [inference]

Rho protein signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction

regulation of biological quality [inference]

regulation by virus of viral protein levels in host cell [inference]

positive regulation by virus of viral protein levels in host cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202 http://purl.obolibrary.org/obo/go/references/0000044 http://purl.obolibrary.org/obo/go/references/0000118
nuclear membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
3-hydroxyacyl-CoA dehydratase activity	IEA	30032202
enzyme binding	IEA	http://purl.obolibrary.org/obo/go/references/0000107
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity	IEA	http://purl.obolibrary.org/obo/go/references/0000003 http://purl.obolibrary.org/obo/go/references/0000107 http://purl.obolibrary.org/obo/go/references/0000116

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

enoyl-CoA hydratase activity [inference]

3-hydroxyacyl-CoA dehydratase activity

(2E)-enoyl-CoA hydratase activity [inference]

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

binding [inference]

protein binding [inference]

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
3-hydroxyacyl-CoA dehydratase activity
fatty acid elongation
fatty acid metabolic process
lipid metabolic process
lyase activity
sphingolipid biosynthetic process
very long-chain fatty acid biosynthetic process
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity