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Guidelines

MIRAGE

UDP-glucose 6-dehydrogenase

Summary

Gene Symbol

UGDH

Organism

Chrysemys picta bellii (western painted turtle)

External Links

NCBI Gene: 101941904
KEGG Gene ID: cpic:101941904
PubChem: 101941904

Annotation

Keyword

Allosteric enzyme
Carbohydrate metabolism
NAD
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C3HJ91

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glycosaminoglycan biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
nucleus	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
UDP-glucose 6-dehydrogenase activity	IEA	22301074 30032202
NAD binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

UDP-glucose 6-dehydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

udp-glucose 6-dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis

Displaying **all 5** entries
Gene Ontology
UDP-glucose 6-dehydrogenase activity
UDP-glucuronate biosynthetic process
glycosaminoglycan biosynthetic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 8** entries
InterPro
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
NAD(P)-binding domain superfamily
UDP-glucose 6-dehydrogenase, eukaryotic type
UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily
UDP-glucose/GDP-mannose dehydrogenase, C-terminal
UDP-glucose/GDP-mannose dehydrogenase, N-terminal
UDP-glucose/GDP-mannose dehydrogenase, dimerisation
UDP-glucose/GDP-mannose dehydrogenase

KEGG BRITE Database

Orthology

K00012

Name

UDPglucose 6-dehydrogenase [EC:1.1.1.22]

References

21961565

Rhea

H₂O + NAD⁺ + UDP-α-D-glucose

H⁺ + NADH + UDP-α-D-glucuronate

Enzyme

1.1.1.22

PMID

Ortholog

Displaying entries **11 - 20** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pongo abelii	100174620		PONAB27450
Taeniopygia guttata	100217939		TAEGU23079
Oryctolagus cuniculus	100355018		RABIT08013
Ailuropoda melanoleuca	100466428		AILME06642
Meleagris gallopavo	100549207		MELGA10161
Nomascus leucogenys	100581327		NOMLE19271
Sus scrofa	100627727		PIGXX33438
Loxodonta africana	100659822		LOXAF13390
Oreochromis niloticus	100692365		ORENI63456
Cavia porcellus	100714768		CAVPO11169

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Supported by JST NBDC Grant Number JPMJND2204

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GlyCosmos Portal v4.3.0

Last updated: August 4, 2025