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triadin

Summary

Gene Symbol

TRDN

Organism

Homo sapiens (human)

External Links

NCBI Gene

10345

KEGG Gene ID

PubChem

10345

Alliance of Genome Resources

HGNC:12261

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Sarcoplasmic reticulum
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q13061
H9ME53
A0A590UJV0
Q8IVK2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
intracellular calcium ion homeostasis	ISS
muscle contraction	TAS
response to bacterium
regulation of cell communication by electrical coupling	TAS
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	ISS

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

intercellular transport [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

membrane organization [inference]

endoplasmic reticulum membrane organization

supramolecular fiber organization [inference]

cytoplasmic microtubule organization

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction

circulatory system process [inference]

heart process [inference]

heart contraction

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

sarcoplasmic reticulum calcium ion transport [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

intercellular transport [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

release of sequestered calcium ion into cytosol by endoplasmic reticulum [inference]

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling involved in cardiac conduction

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling involved in cardiac conduction

regulation of cell communication by electrical coupling

positive regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling involved in cardiac conduction

regulation of cell communication by electrical coupling involved in cardiac conduction [inference]

positive regulation of cell communication by electrical coupling involved in cardiac conduction

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling involved in cardiac conduction

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of striated muscle contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of cardiac muscle cell membrane potential

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
nucleoplasm
endoplasmic reticulum	ISS
cytosol
plasma membrane	EXP
plasma membrane	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

junctional membrane complex

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

sarcoplasmic reticulum membrane

junctional sarcoplasmic reticulum membrane

bounding membrane of organelle [inference]

sarcoplasmic reticulum membrane

junctional sarcoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen [inference]

sarcoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

sarcoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

sarcoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA
protein binding	IPI
protein-macromolecule adaptor activity	ISS
protein-macromolecule adaptor activity	IBA
transmembrane transporter binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060674	catecholaminergic polymorphic ventricular tachycardia	Alliance of Genome Resources
DOID:0060679	catecholaminergic polymorphic ventricular tachycardia 5	Alliance of Genome Resources