GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

glucosylceramidase beta 2

Summary

Gene Symbol

GBA2

Organism

Coturnix japonica (Japanese quail)

External Links

NCBI Gene: 107305799
KEGG Gene ID: cjo:107305799
PubChem: 107305799

Annotation

Keyword

Glycosidase
Lipid metabolism
Membrane
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C2T1M9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
glucosylceramide catabolic process	IEA	22301074
central nervous system development	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

central nervous system development

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glucosylceramidase activity	IEA	22301074
beta-glucosidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosylceramidase activity

glucosidase activity [inference]

beta-glucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

non-lysosomal glucosylceramidase

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
central nervous system development
glucosylceramidase activity
glucosylceramide catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lipid metabolic process

Displaying **all 5** entries
InterPro
Beta-glucosidase GBA2-type
Glycosyl-hydrolase family 116, N-terminal
Glycosyl-hydrolase family 116, catalytic region
Six-hairpin glycosidase superfamily
Six-hairpin glycosidase-like superfamily

KEGG BRITE Database

Orthology

K17108

Name

non-lysosomal glucosylceramidase [EC:3.2.1.45]

References

Rhea

H₂O + a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine

D-glucose + an N-acylsphing-4-enine

Enzyme

3.2.1.45

PMID

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.3.0

Last updated: August 4, 2025