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kinesin family member 1C

Summary

Gene Symbol

KIF1C

Organism

Homo sapiens (human)

External Links

NCBI Gene

10749

KEGG Gene ID

PubChem

10749

Alliance of Genome Resources

HGNC:6317

Annotation

Keyword

3D-structure
ATP-binding
Coiled coil
Cytoskeleton
Disease variant
Methylation
Microtubule
Motor protein
Neurodegeneration
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
O43896

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	TAS
microtubule-based movement	IEA
vesicle-mediated transport	IBA
anterograde neuronal dense core vesicle transport	ISS
retrograde neuronal dense core vesicle transport	ISS

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

vesicle-mediated transport

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

establishment of localization in cell [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

organelle localization [inference]

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde neuronal dense core vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

dense core granule cytoskeletal transport [inference]

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GO Term	Evidence Code	PMID
cytoplasm	IBA
endoplasmic reticulum	TAS
Golgi apparatus	TAS
Golgi apparatus	IEA
cytoskeleton	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical structure [inference]

cytoplasm

neuron projection cytoplasm [inference]

axon cytoplasm

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA
cytoskeletal motor activity	TAS
cytoskeletal motor activity	IEA
microtubule motor activity	IEA
protein binding	IPI

GO Hierarchy

molecular function

cytoskeletal motor activity

microtubule motor activity

plus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

polypeptide conformation or assembly isomerase activity [inference]

microtubule motor activity

plus-end-directed microtubule motor activity

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

plus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinesin-like protein

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding

Displaying entries **1 - 10** of 11 in total

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InterPro
Forkhead-associated (FHA) domain
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-associated
Kinesin-like KIF1-type
Kinesin-like
P-loop containing nucleoside triphosphate hydrolase
PH-like domain superfamily
Pleckstrin homology domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050941	spastic ataxia 2	Alliance of Genome Resources

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	16562	MGI:1098260

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements