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Guidelines

MIRAGE

aldehyde dehydrogenase 1 family, member L1

Summary

Gene Symbol

Aldh1l1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

107747

KEGG Gene ID

PubChem

107747

Alliance of Genome Resources

MGI:1340024

Annotation

Keyword

Acetylation
Cytoplasm
NADP
One-carbon metabolism
Oxidoreductase
Phosphopantetheine
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8R0Y6	Aldehyde dehydrogenase family 1 member L1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
aldehyde metabolic process	IBA
one-carbon metabolic process	IEA
NADPH regeneration	ISS
NADPH regeneration	ISO
NADPH regeneration	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration

modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

tetrahydrofolate metabolic process [inference]

10-formyltetrahydrofolate metabolic process [inference]

10-formyltetrahydrofolate catabolic process

tetrahydrofolate interconversion

folic acid metabolic process

modified amino acid catabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

catabolic process [inference]

modified amino acid catabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

pteridine-containing compound catabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

10-formyltetrahydrofolate catabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

tetrahydrofolate metabolic process [inference]

10-formyltetrahydrofolate metabolic process [inference]

10-formyltetrahydrofolate catabolic process

tetrahydrofolate interconversion

folic acid metabolic process

pteridine-containing compound catabolic process [inference]

folic acid-containing compound catabolic process [inference]

10-formyltetrahydrofolate catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

10-formyltetrahydrofolate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

10-formyltetrahydrofolate metabolic process [inference]

10-formyltetrahydrofolate catabolic process

dicarboxylic acid catabolic process [inference]

10-formyltetrahydrofolate catabolic process

folic acid metabolic process

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

10-formyltetrahydrofolate catabolic process

one-carbon metabolic process

tetrahydrofolate interconversion

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

10-formyltetrahydrofolate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
mitochondrion	IBA
mitochondrion	HDA
cytosol	ISS
cytosol	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
catalytic activity	IEA
aldehyde dehydrogenase (NAD+) activity	IMP
aldehyde dehydrogenase (NAD+) activity	IBA
aldehyde dehydrogenase [NAD(P)+] activity	ISO
protein binding	IPI

GO Hierarchy

molecular function

catalytic activity

oxidoreductase activity

oxidoreductase activity, acting on the CH-NH group of donors [inference]

oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [inference]

formyltetrahydrofolate dehydrogenase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

aldehyde dehydrogenase [NAD(P)+] activity

binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026