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prosaposin

Summary

Gene Symbol

PSAP

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108516862

KEGG Gene ID

rbb:108516862

PubChem

108516862

Annotation

Keyword

Disulfide bond
Glycoprotein
Lysosome
Reference proteome
Repeat
Secreted
Signal
Sphingolipid metabolism

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6LDE8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sphingolipid metabolic process	IEA
lysosomal transport	IEA
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IEA
regulation of lipid metabolic process	IEA
ganglioside GM1 transport to membrane	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

localization within membrane [inference]

ganglioside GM1 transport to membrane

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

ceramide transport [inference]

ganglioside GM1 transport to membrane

glycolipid transport [inference]

ganglioside GM1 transport to membrane

organic acid transport [inference]

carboxylic acid transport [inference]

ganglioside GM1 transport to membrane

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

nitrogen compound transport [inference]

ceramide transport [inference]

ganglioside GM1 transport to membrane

carbohydrate derivative transport [inference]

glycolipid transport [inference]

ganglioside GM1 transport to membrane

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

localization within membrane [inference]

ganglioside GM1 transport to membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

regulation of metabolic process [inference]

regulation of primary metabolic process [inference]

regulation of lipid metabolic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
obsolete extracellular space
lysosome	IEA
late endosome	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protease binding	IEA
phospholipid binding	IEA
protein homodimerization activity	IEA
scaffold protein binding	IEA
ganglioside GM1 binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

protease binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

scaffold protein binding

lipid binding [inference]

phospholipid binding

sphingolipid binding [inference]

glycosphingolipid binding [inference]

ganglioside binding [inference]

ceramide binding [inference]

ganglioside binding [inference]

glycolipid binding [inference]

glycosphingolipid binding [inference]

ganglioside binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

ganglioside GM3 binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

ganglioside GM3 binding

carbohydrate derivative binding [inference]

glycolipid binding [inference]

glycosphingolipid binding [inference]

ganglioside binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K12382

Name

saposin

References

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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