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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

hydroxysteroid 17-beta dehydrogenase 1

Summary

Gene Symbol

HSD17B1

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108518333

KEGG Gene ID

rbb:108518333

PubChem

108518333

Annotation

Keyword

Cytoplasm
Lipid metabolism
NADP
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6KR96

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
estrogen biosynthetic process	IEA
lysosome organization
skeletal muscle tissue development
gene expression
adipose tissue development

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

testosterone biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

macromolecule biosynthetic process [inference]

gene expression

hormone biosynthetic process [inference]

estrogen biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

testosterone biosynthetic process

olefinic compound biosynthetic process [inference]

testosterone biosynthetic process

ketone metabolic process [inference]

ketone biosynthetic process [inference]

testosterone biosynthetic process

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

testosterone biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

testosterone biosynthetic process

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

small molecule metabolic process [inference]

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

testosterone biosynthetic process

olefinic compound metabolic process [inference]

olefinic compound biosynthetic process [inference]

testosterone biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

striated muscle tissue development [inference]

skeletal muscle tissue development

connective tissue development [inference]

adipose tissue development

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
estradiol 17-beta-dehydrogenase [NAD(P)+] activity	IEA
protein homodimerization activity	IEA
NADP+ binding	IEA
17-beta-hydroxysteroid dehydrogenase (NADP+) activity	IEA
estradiol binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

lipid binding [inference]

steroid binding [inference]

estradiol binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

NADP+ binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding [inference]

NADP+ binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding [inference]

NADP+ binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00044

Name

17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]

References

Rhea

17β-estradiol + NAD⁺

H⁺ + estrone + NADH

Enzyme

1.1.1.62

PMID

17β-estradiol + NADP⁺

H⁺ + estrone + NADPH

Enzyme

1.1.1.62

PMID

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026