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sterol O-acyltransferase 2

Summary

Gene Symbol

SOAT2

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108521617

KEGG Gene ID

rbb:108521617

PubChem

108521617

Annotation

Keyword

Acyltransferase
Cholesterol metabolism
Endoplasmic reticulum
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6ML73

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
cholesterol metabolic process	IEA
cholesterol storage
cholesterol efflux	IEA
very-low-density lipoprotein particle assembly	IEA
cholesterol homeostasis	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

very-low-density lipoprotein particle assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

very-low-density lipoprotein particle assembly

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

very-low-density lipoprotein particle assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

very-low-density lipoprotein particle assembly

nutrient storage [inference]

lipid storage [inference]

cholesterol storage

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

very-low-density lipoprotein particle assembly

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal absorption [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
brush border	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

cluster of actin-based cell projections [inference]

brush border

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fatty-acyl-CoA binding	IEA
cholesterol binding	IEA
cholesterol O-acyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

sterol O-acyltransferase activity [inference]

cholesterol O-acyltransferase activity

binding [inference]

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

fatty acid derivative binding [inference]

fatty-acyl-CoA binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

alcohol binding [inference]

cholesterol binding

heterocyclic compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

nucleoside phosphate binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

sulfur compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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