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sterol-C5-desaturase

Summary

Gene Symbol

SC5D

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108523218

KEGG Gene ID

rbb:108523218

PubChem

108523218

Annotation

Keyword

Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6MB24

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process via lathosterol	IEA
negative regulation of ferroptosis	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via lathosterol

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of ferroptosis

regulation of cellular process [inference]

regulation of programmed cell death [inference]

negative regulation of programmed cell death [inference]

negative regulation of ferroptosis

regulation of ferroptosis [inference]

negative regulation of ferroptosis

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of ferroptosis

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA
oxidoreductase activity	IEA
delta7-sterol 5(6)-desaturase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [inference]

sterol desaturase activity [inference]

delta7-sterol 5(6)-desaturase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00227

Name

Delta7-sterol 5-desaturase [EC:1.14.19.20]

References

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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Annotation

KEGG BRITE Database

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Acknowledgements