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sorbitol dehydrogenase

Summary

Gene Symbol

SORD

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108530135

KEGG Gene ID

rbb:108530135

PubChem

108530135

Annotation

Keyword

Carbohydrate metabolism
Flagellum
Metal-binding
NAD
Oxidoreductase
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6L1F3	L-iditol 2-dehydrogenase Polyol dehydrogenase Xylitol dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
D-sorbitol catabolic process	IEA
D-glucuronate catabolic process to D-xylulose 5-phosphate
flagellated sperm motility	IEA
fructose biosynthetic process	IEA
xylitol catabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

organophosphate metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

hexitol metabolic process [inference]

D-sorbitol metabolic process [inference]

D-sorbitol catabolic process

hexitol catabolic process [inference]

D-sorbitol catabolic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

pentitol metabolic process [inference]

pentitol catabolic process [inference]

xylitol catabolic process

xylitol metabolic process [inference]

xylitol catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

alcohol metabolic process [inference]

polyol metabolic process [inference]

hexitol metabolic process [inference]

D-sorbitol metabolic process [inference]

D-sorbitol catabolic process

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol metabolic process [inference]

pentitol catabolic process [inference]

xylitol catabolic process

xylitol metabolic process [inference]

xylitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

D-sorbitol catabolic process

pentitol catabolic process [inference]

xylitol catabolic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

carbohydrate derivative metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytosol	IEA
motile cilium	IEA
mitochondrial membrane	IEA
extracellular exosome	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

organelle membrane [inference]

mitochondrial membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
L-iditol 2-dehydrogenase (NAD+) activity	IEA
zinc ion binding	IEA
identical protein binding	IEA
D-xylulose reductase activity	IEA
NAD binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity [inference]

L-iditol 2-dehydrogenase (NAD+) activity

D-xylulose reductase activity

hexitol dehydrogenase activity [inference]

D-xylulose reductase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00008

Name

L-iditol 2-dehydrogenase [EC:1.1.1.14]

References

Rhea

RHEA:20433

xylitol + NAD⁺

H⁺ + D-xylulose + NADH

Enzyme

1.1.1.9

PMID

17216457

RHEA:10160

L-iditol + NAD⁺

keto-L-sorbose + H⁺ + NADH

Enzyme

1.1.1.14

PMID

RHEA:33031

H⁺ + keto-D-fructose + NADH

D-sorbitol + NAD⁺

Enzyme

1.1.1.14

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements