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Guidelines

MIRAGE

Fc epsilon receptor II

Summary

Gene Symbol

FCER2

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108534535

KEGG Gene ID

rbb:108534535

PubChem

108534535

Annotation

Keyword

Calcium
Coiled coil
Disulfide bond
Glycoprotein
Mannose-binding
Metal-binding
Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2K6JWM8
A0A2K6JWN7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
B cell antigen processing and presentation	IEA
positive regulation of humoral immune response mediated by circulating immunoglobulin
positive regulation of gene expression	IEA
Fc-gamma receptor signaling pathway involved in phagocytosis	IEA
macrophage activation	IEA

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

antigen processing and presentation [inference]

B cell antigen processing and presentation

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

positive regulation of humoral immune response [inference]

positive regulation of humoral immune response mediated by circulating immunoglobulin

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

Displaying **all 2** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
protease binding	IEA
D-mannose binding
low-affinity IgE receptor activity	IEA
IgE binding	IEA
signaling receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

protease binding

carbohydrate binding [inference]

monosaccharide binding [inference]

D-mannose binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

monosaccharide binding [inference]

D-mannose binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

IgE binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

immunoglobulin receptor activity [inference]

IgE receptor activity [inference]

low-affinity IgE receptor activity

immune receptor activity [inference]

immunoglobulin receptor activity [inference]

IgE receptor activity [inference]

low-affinity IgE receptor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K06468

Name

low affinity immunoglobulin epsilon Fc receptor

References

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026