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cytochrome P450 family 11 subfamily B member 2

Summary

Gene Symbol

CYP11B2

Organism

Rhinopithecus bieti (black snub-nosed monkey)

External Links

NCBI Gene

108536550

KEGG Gene ID

rbb:108536550

PubChem

108536550

Annotation

Keyword

Heme
Membrane
Mitochondrion
Monooxygenase
Reference proteome
Steroidogenesis
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6JTQ3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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GO Term	Evidence Code	PMID
regulation of blood volume by renal aldosterone	IEA
glucocorticoid biosynthetic process	IEA
cholesterol metabolic process	IEA
aldosterone biosynthetic process	IEA
cortisol metabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

cortisol biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

tertiary alcohol biosynthetic process [inference]

cortisol biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

olefinic compound biosynthetic process [inference]

ketone metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

cortisol biosynthetic process

ketone biosynthetic process [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

cortisol biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

glucocorticoid metabolic process [inference]

glucocorticoid biosynthetic process

cortisol biosynthetic process

cortisol metabolic process

cortisol biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

cortisol biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

primary alcohol biosynthetic process [inference]

cortisol metabolic process

cortisol biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

tertiary alcohol biosynthetic process [inference]

cortisol biosynthetic process

tertiary alcohol metabolic process [inference]

cortisol metabolic process

cortisol biosynthetic process

tertiary alcohol biosynthetic process [inference]

cortisol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

tertiary alcohol biosynthetic process [inference]

cortisol biosynthetic process

olefinic compound metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

cortisol biosynthetic process

olefinic compound biosynthetic process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to metal ion [inference]

cellular response to potassium ion

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of blood volume by renal aldosterone

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

response to metal ion [inference]

response to potassium ion [inference]

cellular response to potassium ion

cellular response to metal ion [inference]

cellular response to potassium ion

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to metal ion [inference]

cellular response to potassium ion

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

response to nitrogen compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to metal ion [inference]

cellular response to potassium ion

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of blood volume by renal aldosterone

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure [inference]

regulation of blood volume by renal aldosterone

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA
mitochondrial inner membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
steroid 11-beta-monooxygenase activity	IEA
iron ion binding	IEA
heme binding	IEA
corticosterone 18-monooxygenase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

steroid hydroxylase activity [inference]

steroid 11-beta-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07433

Name

steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]

References

Rhea

RHEA:15629

H⁺ + O₂ + a steroid

H₂O + an 11β-hydroxysteroid

Enzyme

1.14.15.4

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Guidelines

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements