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cleavage and polyadenylation specific factor 6

Summary

Gene Symbol

CPSF6

Organism

Homo sapiens (human)

External Links

NCBI Gene

11052

KEGG Gene ID

PubChem

11052

Alliance of Genome Resources

HGNC:13871

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Direct protein sequencing
Methylation
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q16630	Cleavage and polyadenylation specificity factor 68 kDa subunit Cleavage factor Im complex 68 kDa subunit Pre-mRNA cleavage factor Im 68 kDa subunit Protein HPBRII-4/7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
mRNA processing	IDA
mRNA 3'-end processing	IDA
positive regulation of RNA export from nucleus	IMP
protein tetramerization	IDA
protein heterotetramerization	IDA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

positive regulation of transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

positive regulation of transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
nucleus	EXP
nucleus	IDA
nucleus	IEA
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex

mRNA cleavage and polyadenylation specificity factor complex

ribonucleoprotein complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body [inference]

interchromatin granule

nuclear ribonucleoprotein granule [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nuclear body [inference]

interchromatin granule

nuclear ribonucleoprotein granule [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	IEA
RNA binding	IDA
RNA binding	IEA
RNA binding	HDA
mRNA binding	IDA

GO Hierarchy

mRNA binding

protein binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding [inference]

ribosomal large subunit binding

exon-exon junction complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cleavage and polyadenylation specificity factor subunit

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
mRNA alternative polyadenylation

Displaying **all 5** entries
InterPro
CPSF6/7 family
Cleavage and polyadenylation specificity factor subunit 6, RNA recognition motif
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily