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MIRAGE
cholinergic receptor nicotinic alpha 3 subunit
Summary
- Gene Symbol
-
- CHRNA3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Ligand-gated ion channel
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Signal
- Synapse
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P32297 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of membrane potential |
|
|
| regulation of dendrite morphogenesis |
|
|
| membrane depolarization |
|
|
| membrane depolarization |
|
|
| excitatory postsynaptic potential |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleolus |
|
|
| endoplasmic reticulum |
|
|
| endoplasmic reticulum |
|
|
| Golgi apparatus |
|
|
| Golgi apparatus |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| ligand-gated monoatomic ion channel activity |
|
|
| acetylcholine receptor activity |
|
|
| acetylcholine receptor activity |
|
|
| acetylcholine-gated monoatomic cation-selective channel activity |
|
|
| acetylcholine-gated monoatomic cation-selective channel activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acetylcholine receptor subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:10534 | stomach cancer | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:1324 | lung cancer | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:3905 | lung carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:9975 | cocaine dependence | |
| DOID:5409 | lung small cell carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 110834 | MGI:87887 | |
| 180936 | WB:WBGene00000042 | |
| 172105 | WB:WBGene00006774 | |
| 172150 | WB:WBGene00006797 | |
| 178269 | WB:WBGene00002974 | |
| 42919 | FB:FBgn0000039 | |
| 42920 | FB:FBgn0004118 |
