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synuclein, beta

Summary

Gene Symbol

Sncb

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

113893

PubChem

113893

Alliance of Genome Resources

RGD:70992

Annotation

Keyword

Cytoplasm
Direct protein sequencing
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q63754	Phosphoneuroprotein 14

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
chemical synaptic transmission	ISO
chemical synaptic transmission	IBA
dopamine metabolic process	ISO
negative regulation of neuron apoptotic process	ISO
synaptic vesicle endocytosis	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

import into cell [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

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GO Term	Evidence Code	PMID
cytoplasm	IBA
cytoplasm	IEA
inclusion body	ISO
inclusion body	IEA
growth cone	IDA	12821390

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body

cytoplasm

cytosol [inference]

cytosolic region [inference]

presynaptic cytosol

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
calcium ion binding	ISO
calcium ion binding	IEA
alpha-tubulin binding	IDA	18800064
transition metal ion binding	ISO
beta-tubulin binding	IDA	18800064

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding

copper ion binding [inference]

cuprous ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Synuclein

Functional Category

B: Chromatin structure and dynamics
I: Lipid transport and metabolism

Displaying **all 3** entries
Gene Ontology
chemical synaptic transmission
cuprous ion binding
synapse organization

Displaying **all 2** entries
InterPro
Beta-synuclein
Synuclein

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
growth cone	PMID:12821390
axon terminus	PMID:12127102
neuronal cell body	PMID:11716559
terminal bouton	PMID:10777786

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13141	uveitis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 54 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6620	Xenbase:XB-GENE-973307	HUMAN82422
Mus musculus	104069	Xenbase:XB-GENE-973307	MOUSE11180
Xenopus tropicalis	113893	Xenbase:XB-GENE-973307
Canis lupus familiaris	479279		CANLF14784
Bos taurus	508421		BOVIN33143
Macaca mulatta	697484		MACMU38172
Pan troglodytes	736255		PANTR36905
Sus scrofa	100127169		PIGXX19201
Callithrix jacchus	100410405		CALJA26776
Pongo abelii	100456125		PONAB28982

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements