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MIRAGE
cholinergic receptor nicotinic beta 1 subunit

Summary
Gene Symbol
  • CHRNB1
Organism
Homo sapiens (human)
NCBI Gene
1140
PubChem
1140
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Cell membrane
  • Congenital myasthenic syndrome
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Ligand-gated ion channel
  • Phosphoprotein
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
P11230
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 16 in total
GO Term Evidence Code PMID
postsynaptic membrane organization
monoatomic cation transport
muscle contraction
signal transduction
chemical synaptic transmission
GO Hierarchy
Displaying entries 1 - 5 of 10 in total
GO Term Evidence Code PMID
transmembrane signaling receptor activity
protein binding
channel activity
ligand-gated monoatomic ion channel activity
acetylcholine receptor activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
acetylcholine receptor subunit
Functional Category
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
  • X: Mobilome: prophages, transposons
Displaying all 5 entries
Gene Ontology
excitatory postsynaptic potential
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
regulation of postsynaptic membrane potential
Displaying all 8 entries
InterPro
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel
Nicotinic acetylcholine receptor
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0110680 congenital myasthenic syndrome 2C
DOID:0110681 congenital myasthenic syndrome 2A
Ortholog
Displaying entry 101 - 101 of 101 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
118301418 SCOMX24995
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025