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aquaporin 5

Summary

Gene Symbol

Aqp5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11830

PubChem

11830

Alliance of Genome Resources

MGI:106215

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Glycoprotein
Reference proteome
Repeat
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9WTY4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
water transport	ISS
water transport	ISO
water transport	TAS	11066060
water transport	IMP	15557451
water transport	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

secretion by tissue [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

hypotonic response [inference]

cellular hypotonic response

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

response to abiotic stimulus [inference]

response to osmotic stress [inference]

hypotonic response [inference]

cellular hypotonic response

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular hypotonic response

localization [inference]

establishment of localization [inference]

transport [inference]

gas transport [inference]

carbon dioxide transport

fluid transport [inference]

water transport

secretion [inference]

body fluid secretion [inference]

secretion by tissue [inference]

transmembrane transport

organic substance transport [inference]

water transport

one-carbon compound transport [inference]

carbon dioxide transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	16107722
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	TAS	11066060
plasma membrane	IDA	11891232 12042359 16107722

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

plasma membrane region [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	18696337
water channel activity	ISS
water channel activity	ISO
water channel activity	TAS	11066060
water channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

water transmembrane transporter activity [inference]

water channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

water channel activity

salt transmembrane transporter activity [inference]

water transmembrane transporter activity [inference]

water channel activity

binding [inference]

protein binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Aquaporin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
water channel activity

Displaying **all 3** entries
InterPro
Aquaporin-like
Major intrinsic protein, conserved site
Major intrinsic protein

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10140	dry eye syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 64** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Tursiops truncatus	117314104	TURTR11470
Balaenoptera musculus	118902747	BALMU03575
Panthera leo	122224532	PANLE17948
Ursus americanus	123794636	URSAM25152

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements