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Standards Ontologies Notations
Guidelines
MIRAGE
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Summary
Gene Symbol
  • Cacna1a
Organism
Mus musculus (house mouse)
NCBI Gene
12286
PubChem
12286
Alliance of Genome Resources
Annotation
Keyword
  • Calcium channel
  • Cell membrane
  • Coiled coil
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Transmembrane helix
  • Voltage-gated channel
Proteins
Displaying all 7 entries
UniProt Protein Name
E9Q1R5
Q8R5M6
Q8R5M7
A0A571BET0
Q3UHA5
P97445
  • Brain calcium channel I
  • Calcium channel, L type, alpha-1 polypeptide isoform 4
  • Voltage-gated calcium channel subunit alpha Cav2.1
Q3UHN4
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 68 in total
GO Term Evidence Code PMID
system process
monoatomic ion transport
ion transport
calcium ion transport
calcium ion transport
GO Hierarchy
Displaying entries 1 - 5 of 26 in total
GO Term Evidence Code PMID
nucleus
nucleus
cytoplasm
cytoplasm
plasma membrane
GO Hierarchy
Displaying entries 1 - 5 of 19 in total
GO Term Evidence Code PMID
ion channel activity
monoatomic ion channel activity
voltage-gated calcium channel activity
voltage-gated calcium channel activity
voltage-gated calcium channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
voltage-dependent N-type calcium channel subunit alpha-1B
Functional Category
  • E: Amino acid transport and metabolism
  • P: Inorganic ion transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
chemical synaptic transmission
high voltage-gated calcium channel activity
metal ion binding
monoatomic ion channel activity
monoatomic ion transport
Displaying all 5 entries
InterPro
Ion transport domain
Voltage-dependent L-type calcium channel, IQ-associated domain
Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
Voltage-dependent calcium channel, alpha-1 subunit
Voltage-dependent channel domain superfamily
Disease
Disease Ontology
Displaying all 7 entries
DO ID Disease Name Source
DOID:0050214 Lambert-Eaton myasthenic syndrome
DOID:0050704 childhood electroclinical syndrome
DOID:0050753 cerebellar ataxia
DOID:0050835 generalized dystonia
DOID:0050956 spinocerebellar ataxia 6
DOID:0050990 episodic ataxia type 2
DOID:0060178 familial hemiplegic migraine
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026