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Submissions

calcium channel, voltage-dependent, L type, alpha 1C subunit

Summary

Gene Symbol

Cacna1c

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12288

KEGG Gene ID

PubChem

12288

Alliance of Genome Resources

MGI:103013

Annotation

Keyword

Alternative splicing
Calcium channel
Calmodulin-binding
Cell membrane
Cell projection
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Proteomics identification
Reference proteome
Repeat
Transmembrane helix
Voltage-gated channel

Proteins

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UniProt	Protein Name
C7TQ57
C7TQ58
A0A087WSE7
Q01815	Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle MELC-CC Mouse brain class C Voltage-gated calcium channel subunit alpha Cav1.2
F8WJL1
C7TQ62
F7C376
C7TQ60
C7TQ61
A0A087WS40

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 63 in total

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GO Term	Evidence Code	PMID
immune system development	ISO
system process	IEA
monoatomic ion transport	IEA
ion transport	IEA
calcium ion transport	ISO

GO Hierarchy

biological process

immune system process [inference]

immune system development

cellular process [inference]

cell communication

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell communication involved in cardiac conduction

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

vesicle-mediated transport [inference]

exocytosis

regulated exocytosis [inference]

calcium-ion regulated exocytosis

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane transport via high voltage-gated calcium channel

calcium ion transmembrane import into cytosol

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

export from cell [inference]

secretion by cell [inference]

exocytosis

regulated exocytosis [inference]

calcium-ion regulated exocytosis

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

multicellular organismal process [inference]

system process

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction

urinary tract smooth muscle contraction [inference]

urinary bladder smooth muscle contraction [inference]

smooth muscle contraction involved in micturition

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

locomotory behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

walking behavior [inference]

adult walking behavior

visual behavior [inference]

visual learning

adult behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

appendage morphogenesis [inference]

limb morphogenesis [inference]

embryonic limb morphogenesis [inference]

embryonic forelimb morphogenesis

forelimb morphogenesis [inference]

embryonic forelimb morphogenesis

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis [inference]

embryonic forelimb morphogenesis

embryonic morphogenesis [inference]

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis [inference]

embryonic forelimb morphogenesis

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

camera-type eye development

heart development

system development [inference]

immune system development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

calcium ion import

calcium ion import across plasma membrane

calcium ion transmembrane transport

calcium ion transmembrane transport via high voltage-gated calcium channel

calcium ion transmembrane import into cytosol

calcium ion import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane transport via high voltage-gated calcium channel

calcium ion transmembrane import into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane transport via high voltage-gated calcium channel

calcium ion transmembrane import into cytosol

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

vesicle-mediated transport [inference]

exocytosis

regulated exocytosis [inference]

calcium-ion regulated exocytosis

secretion [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

secretion by cell [inference]

exocytosis

regulated exocytosis [inference]

calcium-ion regulated exocytosis

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane transport via high voltage-gated calcium channel

calcium ion transmembrane import into cytosol

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

nitrogen compound transport [inference]

peptide hormone secretion [inference]

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

export from cell [inference]

secretion by cell [inference]

exocytosis

regulated exocytosis [inference]

calcium-ion regulated exocytosis

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

signaling

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of organ growth

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of membrane depolarization

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of organ growth

regulation of cellular process [inference]

regulation of membrane depolarization [inference]

positive regulation of membrane depolarization

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of actin filament-based process [inference]

regulation of actin filament-based movement [inference]

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of striated muscle contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

positive regulation of muscle contraction

regulation of blood circulation [inference]

regulation of heart contraction

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling [inference]

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

cardiac conduction

regulation of heart rate by cardiac conduction

regulation of vasoconstriction

regulation of organ growth

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction

regulation of action potential [inference]

regulation of cardiac muscle cell action potential [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

positive regulation of cytosolic calcium ion concentration

calcium ion transport into cytosol

regulation of blood pressure

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of insulin secretion involved in cellular response to glucose stimulus [inference]

positive regulation of insulin secretion involved in cellular response to glucose stimulus

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of membrane potential

action potential [inference]

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

regulation of membrane depolarization [inference]

positive regulation of membrane depolarization

membrane depolarization [inference]

membrane depolarization during action potential [inference]

membrane depolarization during cardiac muscle cell action potential

regulation of action potential [inference]

regulation of cardiac muscle cell action potential [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity

Displaying entries **1 - 5** of 49 in total

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GO Term	Evidence Code	PMID
caveolar macromolecular signaling complex	IDA
nucleoplasm	ISO
cytoplasm	ISO
plasma membrane	ISS
plasma membrane	ISO

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex

caveolar macromolecular signaling complex

voltage-gated calcium channel complex

L-type voltage-gated calcium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

calcium channel complex [inference]

voltage-gated calcium channel complex

L-type voltage-gated calcium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

calcium channel complex [inference]

voltage-gated calcium channel complex

L-type voltage-gated calcium channel complex

cellular anatomical structure [inference]

membrane

plasma membrane

sarcolemma

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

Z disc

cell junction [inference]

synapse [inference]

glutamatergic synapse

T-tubule

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

cilium

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

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GO Term	Evidence Code	PMID
ion channel activity	IEA
monoatomic ion channel activity	IEA
voltage-gated calcium channel activity	ISO
voltage-gated calcium channel activity	TAS
voltage-gated calcium channel activity	IDA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

voltage-gated calcium channel activity involved in AV node cell action potential

binding [inference]

protein binding

calmodulin binding

cytoskeletal protein binding [inference]

actinin binding [inference]

alpha-actinin binding

enzyme binding

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 2A binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

voltage-dependent calcium channel

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
high voltage-gated calcium channel activity
metal ion binding
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 6** entries
InterPro
Ion transport domain
Voltage-dependent L-type calcium channel, IQ-associated domain
Voltage-dependent calcium channel, L-type, alpha-1 subunit
Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
Voltage-dependent calcium channel, alpha-1 subunit
Voltage-dependent channel domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060173	Timothy syndrome	Alliance of Genome Resources

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	24239	RGD:2245
Drosophila melanogaster	34950	FB:FBgn0001991
Homo sapiens	775	HGNC:1390
Danio rerio	170581	ZFIN:ZDB-GENE-020129-1
Xenopus tropicalis	100488055	Xenbase:XB-GENE-991126

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements