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carnitine palmitoyltransferase 1C

Summary

Gene Symbol

CPT1C

Aliases

CATL1
CPT1P
CPTIC
FLJ23809

Organism

Homo sapiens (human)

External Links

NCBI Gene

126129

HGNC

18540

KEGG Gene ID

hsa:126129

PubChem

126129

Alliance of Genome Resources

HGNC:18540

JoGo

CPT1C

TogoVar

CPT1C

Annotation

Keyword

3D-structure
Acyltransferase
Alternative splicing
Cell projection
Disease variant
Endoplasmic reticulum
Fatty acid metabolism
Hereditary spastic paraplegia
Hydrolase
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KU49	Carnitine O-palmitoyltransferase 1, brain isoform Carnitine palmitoyltransferase 1C Carnitine palmitoyltransferase I
Q8TCG5	Carnitine O-palmitoyltransferase 1, brain isoform Carnitine palmitoyltransferase 1C Carnitine palmitoyltransferase I

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
fatty acid metabolic process	ISS
fatty acid metabolic process	IBA
carnitine metabolic process	ISS
carnitine metabolic process	IBA
macromolecule depalmitoylation	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

carnitine metabolic process

macromolecule metabolic process [inference]

macromolecule modification [inference]

macromolecule deacylation [inference]

macromolecule depalmitoylation

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of postsynaptic membrane neurotransmitter receptor levels

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GO Term	Evidence Code	PMID
mitochondrion	ISS
endoplasmic reticulum	ISS
endoplasmic reticulum	IDA
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

postsynapse

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GO Term	Evidence Code	PMID
catalytic activity	IEA
carnitine O-palmitoyltransferase activity	ISS
protein binding	IPI
palmitoyl-(protein) hydrolase activity	IDA
palmitoyl-(protein) hydrolase activity	IEA

GO Hierarchy

molecular function

catalytic activity

transferase activity [inference]

acyltransferase activity

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

carnitine O-acyltransferase activity [inference]

carnitine O-palmitoyltransferase activity

O-palmitoyltransferase activity [inference]

carnitine O-palmitoyltransferase activity

palmitoyltransferase activity [inference]

O-palmitoyltransferase activity [inference]

carnitine O-palmitoyltransferase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

palmitoyl-(protein) hydrolase activity

palmitoyl hydrolase activity [inference]

palmitoyl-(protein) hydrolase activity

catalytic activity, acting on a protein [inference]

palmitoyl-(protein) hydrolase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K19524

Name

carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]

References

12376098

Rhea

RHEA:19233

H₂O

H⁺ + hexadecanoate

Enzyme

3.1.2.22

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110818	hereditary spastic paraplegia 73	Alliance of Genome Resources

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0000012	Urinary urgency
HP:0000020	Urinary incontinence
HP:0000726	Dementia
HP:0001250	Seizure
HP:0001258	Spastic paraplegia
HP:0001347	Hyperreflexia
HP:0001761	Pes cavus
HP:0002061	Lower limb spasticity
HP:0002064	Spastic gait