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MIRAGE

ELOVL fatty acid elongase 3

Summary

Gene Symbol

Elovl3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12686

KEGG Gene ID

PubChem

12686

Alliance of Genome Resources

MGI:1195976

Annotation

Keyword

Endoplasmic reticulum
Fatty acid biosynthesis
Glycoprotein
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O35949	3-keto acyl-CoA synthase Elovl3 CIN-2 Cold-inducible glycoprotein of 30 kDa ELOVL fatty acid elongase 3 Elongation of very long chain fatty acids protein 3 Very long chain 3-ketoacyl-CoA synthase 3 Very long chain 3-oxoacyl-CoA synthase 3
A0A498WFQ4	Very-long-chain 3-oxoacyl-CoA synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
fatty acid biosynthetic process
unsaturated fatty acid biosynthetic process	IEA
lipid biosynthetic process	IEA
fatty acid elongation, saturated fatty acid	ISO
fatty acid elongation, saturated fatty acid	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

sphingolipid biosynthetic process

fatty acid derivative biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

lipid biosynthetic process

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

sphingolipid biosynthetic process

fatty acid derivative biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty acid derivative metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty acid derivative biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA metabolic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

fatty-acyl-CoA biosynthetic process [inference]

long-chain fatty-acyl-CoA biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	ISS
endoplasmic reticulum	ISO
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fatty acid elongase activity	ISO
fatty acid elongase activity	IBA
fatty acid elongase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

fatty acid elongase activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	39860	FB:FBgn0260960
Homo sapiens	83401	HGNC:18047
Saccharomyces cerevisiae S288C	851087	SGD:S000004364

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026