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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
catechol-O-methyltransferase
Summary
- Gene Symbol
-
- COMT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Catecholamine metabolism
- Cell membrane
- Cytoplasm
- Direct protein sequencing
- Lipid metabolism
- Magnesium
- Metal-binding
- Methyltransferase
- Neurotransmitter degradation
- Phosphoprotein
- Reference proteome
- S-adenosyl-L-methionine
- Schizophrenia
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P21964 |
|
| A0A140VJG8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| behavioral fear response | ||
| response to hypoxia | ||
| synaptic transmission, dopaminergic | ||
| startle response | ||
| response to amphetamine |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| magnesium ion binding | ||
| protein binding | ||
| methyltransferase activity | ||
| O-methyltransferase activity | ||
| catechol O-methyltransferase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- O methyltransferase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- H: Coenzyme transport and metabolism
- J: Translation, ribosomal structure and biogenesis
| Gene Ontology |
|---|
| O-methyltransferase activity |
| catecholamine catabolic process |
| catecholamine metabolic process |
| dopamine metabolic process |
| methylation |
| transferase activity |
| InterPro |
|---|
| Class I-like SAM-dependent O-methyltransferase |
| S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:0060001 | withdrawal disorder | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:10283 | prostate cancer | |
| DOID:10763 | hypertension | |
| DOID:10933 | obsessive-compulsive disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:12129 | bulimia nervosa | |
| DOID:12306 | vitiligo |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000023 | Inguinal hernia |
| HP:0000028 | Cryptorchidism |
| HP:0000047 | Hypospadias |
| HP:0000076 | Vesicoureteral reflux |
| HP:0000089 | Renal hypoplasia |
| HP:0000113 | Polycystic kidney dysplasia |
| HP:0000130 | Abnormality of the uterus |
| HP:0000160 | Narrow mouth |
| HP:0000164 | Abnormality of the dentition |
| Disease ID | Disease Name |
|---|---|
| OMIM:167870 |
|
| ORPHA:567 |
|
| OMIM:181500 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1312 | Xenbase:XB-GENE-948947 | ||
| 12846 | Xenbase:XB-GENE-948947 | MOUSE19552 | |
| 24267 | Xenbase:XB-GENE-5865481 | RATNO04095 | |
| 445450 | CANLF10595 | ||
| 458655 | PANTR25982 | ||
| 561372 | Xenbase:XB-GENE-5865481 | DANRE42593 | |
| 565370 | ZFIN:ZDB-GENE-040724-164 | DANRE01869 | |
| 712548 | MACMU00872 | ||
| 100155530 | PIGXX07450 | ||
| 100223814 | TAEGU05974 |
