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Guidelines

MIRAGE

endothelin receptor type B

Summary

Gene Symbol

Ednrb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13618

KEGG Gene ID

PubChem

13618

Alliance of Genome Resources

MGI:102720

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P48302	Endothelin receptor non-selective type

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **100** in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	ISO
negative regulation of transcription by RNA polymerase II	IDA
negative regulation of transcription by RNA polymerase II	IEA
neural crest cell migration	IMP
positive regulation of protein phosphorylation	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

macrophage chemotaxis

mononuclear cell migration [inference]

macrophage migration [inference]

macrophage chemotaxis

myeloid leukocyte migration [inference]

macrophage migration [inference]

macrophage chemotaxis

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

metabolic process [inference]

aldehyde metabolic process [inference]

aldosterone metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ketone metabolic process [inference]

aldosterone metabolic process

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

aldosterone metabolic process

mineralocorticoid metabolic process [inference]

aldosterone metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparin proteoglycan metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

lipid metabolic process [inference]

steroid metabolic process [inference]

C21-steroid hormone metabolic process [inference]

aldosterone metabolic process

mineralocorticoid metabolic process [inference]

aldosterone metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparin proteoglycan metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

aldosterone metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process [inference]

cGMP biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

olefinic compound metabolic process [inference]

aldosterone metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparin proteoglycan metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process [inference]

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

muscle cell differentiation [inference]

smooth muscle cell differentiation [inference]

enteric smooth muscle cell differentiation

pigment cell differentiation [inference]

melanocyte differentiation

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

leukocyte migration [inference]

leukocyte chemotaxis [inference]

macrophage chemotaxis

mononuclear cell migration [inference]

macrophage migration [inference]

macrophage chemotaxis

myeloid leukocyte migration [inference]

macrophage migration [inference]

macrophage chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

macrophage chemotaxis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

protein transmembrane transport

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

renin secretion into blood stream

signal release [inference]

renin secretion into blood stream

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

phasic smooth muscle contraction [inference]

vein smooth muscle contraction

vascular associated smooth muscle contraction [inference]

vein smooth muscle contraction

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasoconstriction

vascular associated smooth muscle contraction [inference]

vein smooth muscle contraction

vasodilation

blood circulation

renal system process [inference]

renal sodium ion transport [inference]

renal sodium ion absorption

regulation of urine volume [inference]

positive regulation of urine volume

renal absorption [inference]

renal sodium ion absorption

renal protein absorption [inference]

renal albumin absorption

renal tubular secretion [inference]

renal sodium excretion

excretion [inference]

renal tubular secretion [inference]

renal sodium excretion

multicellular organismal response to stress [inference]

response to pain

developmental process [inference]

anatomical structure development [inference]

posterior midgut development

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

system development [inference]

pharynx development [inference]

chordate pharynx development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

muscle cell differentiation [inference]

smooth muscle cell differentiation [inference]

enteric smooth muscle cell differentiation

pigment cell differentiation [inference]

melanocyte differentiation

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

macrophage chemotaxis

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

sodium ion homeostasis

developmental pigmentation

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to endothelin

response to chemical [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to endothelin

response to lipid [inference]

response to lipopolysaccharide

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to endothelin

response to oxygen-containing compound [inference]

response to lipopolysaccharide

cellular response to lipopolysaccharide

response to peptide hormone [inference]

response to endothelin

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to salt [inference]

response to sodium phosphate

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein secretion [inference]

renin secretion into blood stream

protein transmembrane transport

protein localization to extracellular region [inference]

protein secretion [inference]

renin secretion into blood stream

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

renal sodium ion transport [inference]

renal sodium ion absorption

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

protein transport [inference]

protein secretion [inference]

renin secretion into blood stream

protein transmembrane transport

fluid transport [inference]

epithelial fluid transport

secretion [inference]

secretion by cell [inference]

protein secretion [inference]

renin secretion into blood stream

signal release [inference]

renin secretion into blood stream

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

protein transmembrane transport

transepithelial transport [inference]

epithelial fluid transport

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

renin secretion into blood stream

signal release [inference]

renin secretion into blood stream

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

renin secretion into blood stream

protein transmembrane transport

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

renin secretion into blood stream

biological regulation [inference]

regulation of pH

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of multicellular organismal process [inference]

positive regulation of penile erection

positive regulation of reproductive process [inference]

positive regulation of penile erection

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of fever generation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of fever generation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of neuron differentiation [inference]

regulation of neuron maturation [inference]

negative regulation of neuron maturation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of cell maturation [inference]

regulation of neuron maturation [inference]

negative regulation of neuron maturation

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

negative regulation of protein metabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

negative regulation of protein metabolic process

regulation of cell population proliferation [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of neuron differentiation [inference]

regulation of neuron maturation [inference]

negative regulation of neuron maturation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of cell maturation [inference]

regulation of neuron maturation [inference]

negative regulation of neuron maturation

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of neuron maturation

regulation of multicellular organismal process [inference]

regulation of heat generation [inference]

regulation of fever generation

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate

positive regulation of multicellular organismal process [inference]

positive regulation of penile erection

regulation of penile erection [inference]

positive regulation of penile erection

regulation of reproductive process [inference]

regulation of penile erection [inference]

positive regulation of penile erection

positive regulation of reproductive process [inference]

positive regulation of penile erection

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

aldosterone metabolic process

mineralocorticoid metabolic process [inference]

aldosterone metabolic process

regulation of body fluid levels [inference]

regulation of urine volume [inference]

positive regulation of urine volume

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasoconstriction

vascular associated smooth muscle contraction [inference]

vein smooth muscle contraction

vasodilation

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane

organelle membrane [inference]

nuclear membrane

Displaying entries **6 - 10** of 11 in total

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1

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3

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GO Term	Evidence Code	PMID
endothelin receptor activity	IEA
protein binding	IPI
peptide hormone binding	ISO
peptide hormone binding	IEA
type 1 angiotensin receptor binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

angiotensin receptor binding [inference]

type 1 angiotensin receptor binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

endothelin receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

endothelin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110953	Waardenburg syndrome type 4A	Alliance of Genome Resources
DOID:10487	Hirschsprung's disease	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	50672	RGD:2536
Homo sapiens	1910	HGNC:3180

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Last updated: April 6, 2026