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MIRAGE
FMS-like tyrosine kinase 3
Summary
- Gene Symbol
-
- Flt3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Coiled coil
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Immunoglobulin domain
- Magnesium
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| leukocyte homeostasis |
|
|
| positive regulation of protein phosphorylation |
|
|
| myeloid progenitor cell differentiation |
|
|
| myeloid progenitor cell differentiation |
|
|
| lymphoid progenitor cell differentiation |
|
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum |
|
|
| endoplasmic reticulum lumen |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| external side of plasma membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity |
|
|
| protein tyrosine kinase activity |
|
|
| protein tyrosine kinase activity |
|
|
| transmembrane receptor protein tyrosine kinase activity |
|
|
| transmembrane receptor protein tyrosine kinase activity |
|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:9119 | acute myeloid leukemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 175182 | WB:WBGene00006894 | |
| 2322 | HGNC:3765 |
