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polypeptide N-acetylgalactosaminyltransferase 1

Summary

Gene Symbol

Galnt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14423

KEGG Gene ID

mmu:14423

PubChem

14423

Alliance of Genome Resources

MGI:894693

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Reference proteome
Secreted
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UFE4
O08912	Polypeptide GalNAc transferase 1 Protein-UDP acetylgalactosaminyltransferase 1 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein O-linked glycosylation	ISO
protein O-linked glycosylation	IDA
protein O-linked glycosylation	IBA
protein O-linked glycosylation via N-acetyl-galactosamine	ISO
protein O-linked glycosylation via N-acetyl-galactosamine	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
Golgi apparatus	ISO
Golgi apparatus	IBA
Golgi apparatus	IEA
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
polypeptide N-acetylgalactosaminyltransferase activity	ISO
polypeptide N-acetylgalactosaminyltransferase activity	IDA
polypeptide N-acetylgalactosaminyltransferase activity	IBA
polypeptide N-acetylgalactosaminyltransferase activity	IEA
hexosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

catalytic activity, acting on a protein [inference]

polypeptide N-acetylgalactosaminyltransferase activity

binding [inference]

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

N-acetylgalactosaminyltransferase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
polypeptide N-acetylgalactosaminyltransferase activity
protein O-linked glycosylation
transferase activity

Displaying **all 5** entries
InterPro
Glycosyltransferase 2-like
N-acetylgalactosaminyltransferase
Nucleotide-diphospho-sugar transferases
Ricin B, lectin domain
Ricin B-like lectins

KEGG BRITE Database

Orthology

K00710

Name

polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]

References

9295285

Rhea

RHEA:23956

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

RHEA:52424

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:4079	heart valve disease	Alliance of Genome Resources

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	79214	RGD:620358
Caenorhabditis elegans	176112	WB:WBGene00001628
Drosophila melanogaster	326151	FB:FBgn0031681
Homo sapiens	2589	HGNC:4123
Danio rerio	559073	ZFIN:ZDB-GENE-030131-2360
Xenopus tropicalis	594943	Xenbase:XB-GENE-1013398

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements