GlyCosmos Portal

Annotation

Keyword

Acetylation
Cytoplasm
Endoplasmic reticulum
Hydrolase
Inflammatory response
Innate immunity
Lyase
Metal-binding
Nucleus
Peroxisome
Phosphoprotein
Proteomics identification
Reference proteome
Transferase
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IV20	Adenosine deaminase LACC1 Fatty acid metabolism-immunity nexus Guanosine phosphorylase LACC1 Isocyanic acid synthase Laccase domain-containing protein 1 S-methyl-5'-thioadenosine phosphorylase LACC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
pattern recognition receptor signaling pathway	IDA
positive regulation of cytokine production involved in immune response	IDA
inflammatory response
obsolete regulation of cellular pH
regulation of defense response	IEA

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of intracellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

biological regulation [inference]

regulation of pH [inference]

regulation of intracellular pH

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to stress [inference]

regulation of defense response

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of biological quality [inference]

regulation of intracellular pH

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	IEA
cytoplasm	IEA
peroxisome	IDA
peroxisome	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
adenosine deaminase activity	IDA
adenosine deaminase activity	IEA
purine-nucleoside phosphorylase activity	IDA
purine-nucleoside phosphorylase activity	IEA
copper ion binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on diphenols and related substances as donors [inference]

oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

purine-nucleoside phosphorylase activity

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [inference]

adenosine deaminase activity

deaminase activity [inference]

adenosine deaminase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

laccase domain containing 1

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 8** entries
Gene Ontology
2'-deoxyadenosine deaminase activity
S-methyl-5-thioadenosine phosphorylase activity
adenosine deaminase activity
copper ion binding
hydrolase activity
metal ion binding
purine-nucleoside phosphorylase activity
transferase activity

Displaying **all 3** entries
InterPro
Cytotoxic necrotizing factor-like, catalytic
Multi-copper polyphenol oxidoreductase superfamily
Multi-copper polyphenol oxidoreductase

Human Protein Atlas

ENSG00000179630

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Rhea

RHEA:24408

H₂O + H⁺ + adenosine

inosine + NH₄⁺

Enzyme

3.5.4.4

PMID

RHEA:19805

a purine D-ribonucleoside + phosphate

a purine nucleobase + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:36431

a purine 2'-deoxy-D-ribonucleoside + phosphate

a purine nucleobase + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27742

2'-deoxyadenosine + phosphate

adenine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

21672603

RHEA:11852

S-methyl-5'-thioadenosine + phosphate

adenine + S-methyl-5-thio-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

RHEA:27646

inosine + phosphate

hypoxanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:28190

H₂O + H⁺ + 2'-deoxyadenosine

NH₄⁺ + 2'-deoxyinosine

Enzyme

3.5.4.4

PMID

RHEA:27638

xanthosine + phosphate

xanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:27738

2'-deoxyguanosine + phosphate

guanine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27642

adenosine + phosphate

adenine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:24869

5'-deoxyadenosine + phosphate

adenine + 5-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

6164373

RHEA:27750

2'-deoxyinosine + phosphate

hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:13233

guanosine + phosphate

guanine + α-D-ribose 1-phosphate

Enzyme

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:676	systemic juvenile rheumatoid arthritis	Alliance of Genome Resources

The Human Phenotype Ontology

Displaying entries **1 - 10** of 21 in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000988	Skin rash
HP:0001369	Arthritis
HP:0001386	Joint swelling
HP:0001701	Pericarditis
HP:0001744	Splenomegaly
HP:0001894	Thrombocytosis
HP:0001945	Fever
HP:0001974	Leukocytosis
HP:0002027	Abdominal pain