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GPI anchor attachment protein 1

Summary

Gene Symbol

Gpaa1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14731

KEGG Gene ID

PubChem

14731

Alliance of Genome Resources

MGI:1202392

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
GPI-anchor biosynthesis
Glycoprotein
Magnesium
Metal-binding
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9WTK3	GAA1 protein homolog Glycosylphosphatidylinositol anchor attachment 1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
GPI anchor biosynthetic process	ISS
GPI anchor biosynthetic process	IEA
attachment of GPI anchor to protein	ISS
attachment of GPI anchor to protein	ISO
attachment of GPI anchor to protein	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

protein metabolic process [inference]

protein maturation [inference]

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
endoplasmic reticulum	ISO
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IEA
centrosome	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

GPI-anchor transamidase complex

endoplasmic reticulum protein-containing complex [inference]

GPI-anchor transamidase complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

caspase complex [inference]

GPI-anchor transamidase complex

transferase complex [inference]

GPI-anchor transamidase complex

cellular anatomical structure [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
GPI-anchor transamidase activity	TAS
GPI anchor binding	ISS
GPI anchor binding	ISO
GPI anchor binding	IEA
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring nitrogenous groups [inference]

GPI-anchor transamidase activity

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

GPI-anchor transamidase activity

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

GPI-anchor transamidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

GPI-anchor transamidase activity

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

GPI-anchor transamidase activity

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

GPI anchor binding

glycolipid binding [inference]

GPI anchor binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

carbohydrate derivative binding [inference]

glycolipid binding [inference]

GPI anchor binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	31517	FB:FBgn0029818
Homo sapiens	8733	HGNC:4446
Saccharomyces cerevisiae S288C	850777	SGD:S000004078

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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