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glypican 1

Summary

Gene Symbol

Gpc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14733

KEGG Gene ID

PubChem

14733

Alliance of Genome Resources

MGI:1194891

Annotation

Keyword

Cell membrane
Copper
Disulfide bond
Endosome
GPI-anchor
Heparan sulfate
Reference proteome
S-nitrosylation
Secreted
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9QZF2
Q3U379

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
regulation of signal transduction	IEA
Schwann cell differentiation	ISS
Schwann cell differentiation	ISO
cell migration	IBA
heparan sulfate proteoglycan catabolic process	ISS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of fibroblast growth factor receptor signaling pathway [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of localization [inference]

regulation of protein localization [inference]

regulation of protein localization to membrane

regulation of cellular localization [inference]

regulation of protein localization to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of fibroblast growth factor receptor signaling pathway [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of fibroblast growth factor receptor signaling pathway [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

regulation of skeletal muscle cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of fibroblast growth factor receptor signaling pathway [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

regulation of skeletal muscle cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of skeletal muscle cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of fibroblast growth factor receptor signaling pathway

regulation of cellular localization [inference]

regulation of protein localization to membrane

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
nucleoplasm	ISO
endosome	IEA
Golgi lumen	TAS
Golgi lumen	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

Golgi lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

cell body [inference]

neuronal cell body

side of membrane

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
laminin binding	IDA
collagen V binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding [inference]

fibroblast growth factor binding

laminin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

protein-containing complex binding [inference]

collagen binding [inference]

collagen V binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

GlyPicaN

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell migration

Displaying 1 entry
InterPro
Glypican

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	58920	RGD:61853
Drosophila melanogaster	39596	FB:FBgn0041604
Homo sapiens	2817	HGNC:4449
Danio rerio	553367	ZFIN:ZDB-GENE-051120-147
Xenopus tropicalis	779769	Xenbase:XB-GENE-964661