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MIRAGE
cathepsin B

Summary
Gene Symbol
  • CTSB
Organism
Homo sapiens (human)
NCBI Gene
1508
KEGG Gene ID
PubChem
1508
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Lysosome
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal
  • Thiol protease
  • Zymogen
Proteins
Displaying all 2 entries
UniProt Protein Name
P07858
  • APP secretase
  • Cathepsin B1
A0A024R374
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 14 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
proteolysis
thyroid hormone generation
protein catabolic process
GO Hierarchy
Displaying entries 1 - 5 of 21 in total
GO Term Evidence Code PMID
extracellular region
extracellular region
extracellular region
extracellular region
extracellular region
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
cathepsin
Functional Category
  • E: Amino acid transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • P: Inorganic ion transport and metabolism
Displaying all 4 entries
Gene Ontology
cysteine-type endopeptidase activity
hydrolase activity
proteolysis involved in protein catabolic process
proteolysis
Displaying all 7 entries
InterPro
Cysteine peptidase, asparagine active site
Cysteine peptidase, cysteine active site
Cysteine peptidase, histidine active site
Papain-like cysteine peptidase superfamily
Peptidase C1A, papain C-terminal
Peptidase C1A, propeptide
Peptidase C1A
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:9351 diabetes mellitus
Ortholog
Displaying all 4 entries
Species Gene ID Alliance of Genome Resources
13030 MGI:88561
180033 WB:WBGene00000783
179053 WB:WBGene00000784
180931 WB:WBGene00000786
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026