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homeostatic iron regulator

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

15216

PubChem

15216

Alliance of Genome Resources

MGI:109191

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Iron transport
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P70387
Q5SZ87

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 46 in total

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GO Term	Evidence Code	PMID
negative regulation of T cell cytokine production	ISO
negative regulation of T cell cytokine production	IEA
iron ion transport
intracellular iron ion homeostasis	ISO
intracellular iron ion homeostasis	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

hormone biosynthetic process

hormone metabolic process [inference]

hormone biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

small molecule metabolic process [inference]

urate metabolic process

purine-containing compound metabolic process [inference]

urate metabolic process

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to iron ion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

response to stimulus [inference]

response to stress [inference]

response to starvation [inference]

response to metal ion starvation [inference]

response to iron ion starvation

response to nutrient levels [inference]

response to starvation [inference]

response to metal ion starvation [inference]

response to iron ion starvation

response to chemical [inference]

response to metal ion [inference]

response to iron ion

cellular response to iron ion

cellular response to metal ion [inference]

cellular response to iron ion

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to iron ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to iron ion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

transferrin transport

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

transferrin transport

protein transport [inference]

transferrin transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport [inference]

transferrin transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of antigen processing and presentation [inference]

negative regulation of antigen processing and presentation [inference]

negative regulation of antigen processing and presentation of peptide antigen [inference]

negative regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

regulation of antigen processing and presentation of peptide antigen [inference]

negative regulation of antigen processing and presentation of peptide antigen [inference]

negative regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

negative regulation of immune system process [inference]

negative regulation of antigen processing and presentation [inference]

negative regulation of antigen processing and presentation of peptide antigen [inference]

negative regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of CD8-positive, alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell surface

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of iron ion transport

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of antigen processing and presentation [inference]

negative regulation of antigen processing and presentation of peptide antigen [inference]

negative regulation of antigen processing and presentation of peptide antigen via MHC class I [inference]

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell cytokine production

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of CD8-positive, alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

negative regulation of T cell cytokine production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of CD8-positive, alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of T cell cytokine production

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of CD8-positive, alpha-beta T cell activation

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

hormone biosynthetic process

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of molecular function [inference]

regulation of catalytic activity

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space
nucleoplasm	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

HFE-transferrin receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

HFE-transferrin receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton [inference]

cortical actin cytoskeleton [inference]

terminal web

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton [inference]

cortical actin cytoskeleton [inference]

terminal web

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	ISO
signaling receptor binding	IEA
beta-2-microglobulin binding	ISO
beta-2-microglobulin binding	IEA
co-receptor binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

transferrin receptor binding

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter activator activity

transporter regulator activity [inference]

transporter activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

H-2 class II histocompatibility antigen, A beta chain-like

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
immune response

Displaying **all 5** entries
InterPro
Immunoglobulin C1-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
MHC classes I/II-like antigen recognition protein

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111029	hemochromatosis type 1	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements