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MIRAGE
hydroxysteroid 11-beta dehydrogenase 1
Summary
- Gene Symbol
-
- Hsd11b1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Endoplasmic reticulum
- Glycoprotein
- NADP
- Oxidoreductase
- Proteomics identification
- Reference proteome
- Signal-anchor
- Steroid metabolism
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q4JHD9 |
|
| P50172 |
|
| Q3TJI8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucocorticoid biosynthetic process |
|
|
| steroid catabolic process |
|
|
| glucocorticoid catabolic process |
|
|
| glucocorticoid catabolic process |
|
|
| glucocorticoid catabolic process |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum |
|
|
| endoplasmic reticulum membrane |
|
|
| endoplasmic reticulum membrane |
|
|
| endoplasmic reticulum membrane |
|
|
| nuclear membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| steroid binding |
|
|
| steroid binding |
|
|
| protein homodimerization activity |
|
|
| protein homodimerization activity |
|
|
| 7-beta-hydroxysteroid dehydrogenase (NADP+) activity |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- hydroxysteroid (11-beta) dehydrogenase 1
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| oxidoreductase activity |
| InterPro |
|---|
| NAD(P)-binding domain superfamily |
| Short-chain dehydrogenase/reductase SDR |
| Short-chain dehydrogenase/reductase, conserved site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090140 | cortisone reductase deficiency 2 |
