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DAB adaptor protein 2
Summary
- Gene Symbol
-
- DAB2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Apoptosis
- Coated pit
- Cytoplasm
- Cytoplasmic vesicle
- Developmental protein
- Differentiation
- Endocytosis
- Phosphoprotein
- Protein transport
- Proteomics identification
- Reference proteome
- Tumor suppressor
- Wnt signaling pathway
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| receptor-mediated endocytosis |
|
|
| apoptotic process |
|
|
| transforming growth factor beta receptor signaling pathway |
|
|
| integrin-mediated signaling pathway |
|
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of hormone metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibrillar center |
|
|
| cytoplasm |
|
|
| cytoplasm |
|
|
| lysosomal membrane |
|
|
| cytosol |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding |
|
|
| clathrin-cargo adaptor activity |
|
|
| clathrin-cargo adaptor activity |
|
|
| cargo receptor activity |
|
|
| cargo receptor activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- disabled homolog 2
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell differentiation |
| positive regulation of endocytosis |
| receptor-mediated endocytosis |
| InterPro |
|---|
| Disabled homolog 1/2, sulfatide-binding motif |
| Disabled, phosphotyrosine-binding domain |
| PH-like domain superfamily |
| PTB/PI domain |
