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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

integrin alpha 7

Summary

Gene Symbol

Itga7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16404

KEGG Gene ID

PubChem

16404

Alliance of Genome Resources

MGI:102700

Annotation

Keyword

ADP-ribosylation
Calcium
Cell adhesion
Cell shape
Cleavage on pair of basic residues
Disulfide bond
Glycoprotein
Integrin
Metal-binding
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8V5L190
Q3TZS3
G3X9Q1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cell adhesion	ISO
cell adhesion	IMP
cell adhesion	IEA
cell-matrix adhesion	IBA
integrin-mediated signaling pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration

cellular process [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cell-cell adhesion

heterotypic cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

cell motility [inference]

leukocyte migration

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of biological quality [inference]

regulation of cell shape

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cytoplasm	IDA
muscle tendon junction	IDA
integrin complex	ISO
integrin complex	IBA
integrin complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha7-beta1 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alpha7-beta1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha7-beta1 complex

cellular anatomical structure [inference]

plasma membrane [inference]

sarcolemma

cell junction [inference]

synapse [inference]

neuromuscular junction

anchoring junction [inference]

cell-substrate junction [inference]

muscle tendon junction

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
integrin binding	ISO
protein binding	IPI
signaling receptor activity	IBA
laminin binding	ISO
laminin binding	IDA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

laminin binding

cell adhesion molecule binding

integrin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding

integrin binding

extracellular matrix binding [inference]

laminin binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 9** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain, C-terminal cytoplasmic region, conserved site
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin alpha, third immunoglobulin-like domain
Integrin domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110639	congenital muscular dystrophy due to integrin alpha-7 deficiency	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	81008	RGD:71022
Caenorhabditis elegans	176296	WB:WBGene00002081
Drosophila melanogaster	32275	FB:FBgn0004456
Homo sapiens	3679	HGNC:6143

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026