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eukaryotic translation initiation factor 6

Summary

Gene Symbol

Eif6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16418

KEGG Gene ID

PubChem

16418

Alliance of Genome Resources

MGI:1196288

Annotation

Keyword

Cytoplasm
Initiation factor
Nucleus
Phosphoprotein
Reference proteome
Ribosome biogenesis
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O55135	B4 integrin interactor CAB p27(BBP)
Q545K4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
ribosomal subunit export from nucleus	IBA
ribosomal subunit export from nucleus	IEA
maturation of 5.8S rRNA	IBA
maturation of LSU-rRNA	IBA
regulation of glycolytic process	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

translational initiation

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

RNA processing [inference]

rRNA processing [inference]

intercellular transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

ribosome assembly [inference]

cytosolic ribosome assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

assembly of large subunit precursor of preribosome

organelle assembly [inference]

membraneless organelle assembly [inference]

ribosome assembly [inference]

cytosolic ribosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

assembly of large subunit precursor of preribosome

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

assembly of large subunit precursor of preribosome

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal large subunit biogenesis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin

localization [inference]

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

establishment of organelle localization [inference]

ribosomal subunit export from nucleus

organelle localization [inference]

ribosome localization [inference]

ribosomal subunit export from nucleus

establishment of organelle localization [inference]

ribosomal subunit export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

ribosomal subunit export from nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of megakaryocyte differentiation

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of megakaryocyte differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of megakaryocyte differentiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of translation

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of gene expression [inference]

positive regulation of translation

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of catabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process

regulation of ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycolytic process

regulation of phosphorus metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of translation

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of gene expression [inference]

positive regulation of translation

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of reactive oxygen species metabolic process

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of megakaryocyte differentiation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of megakaryocyte differentiation

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IBA
nucleus	IEA
lamin filament	IDA
nucleoplasm	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nucleolus

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

lamin filament

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
translation initiation factor activity	IEA
ribosome binding	ISS
ribosome binding	ISO
ribosome binding	IEA
ribosomal large subunit binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

ribosomal large subunit binding

translation factor activity [inference]

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	173169	WB:WBGene00001234
Homo sapiens	3692	HGNC:6159

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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